Improvements in Resolution of 1H NMR of solids
Magic angle spinning (MAS) in 1H NMR has allowed progress from featureless spectra in static samples to linewidths of a few hundreds of Hertz for powdered solids at the fastest spinning rates available today (100-150 kHz). While this is a remarkable improvement, this level of resolution is still li...
| Main Authors: | , |
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
2023-04-01
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| Series: | CHIMIA |
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| Online Access: | https://www.chimia.ch/chimia/article/view/6950 |
| _version_ | 1797826461386670080 |
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| author | Bruno Simões de Almeida Lyndon Emsley |
| author_facet | Bruno Simões de Almeida Lyndon Emsley |
| author_sort | Bruno Simões de Almeida |
| collection | DOAJ |
| description |
Magic angle spinning (MAS) in 1H NMR has allowed progress from featureless spectra in static samples to linewidths of a few hundreds of Hertz for powdered solids at the fastest spinning rates available today (100-150 kHz). While this is a remarkable improvement, this level of resolution is still limiting to the widespread use of 1H NMR for complex systems. This review will discuss two recent alternative strategies that have significantly improved 1H resolution, when combined with fast MAS. The first is based on anti-z-COSY, a 2D experiment originally used for J decoupling in liquids, which removes residual broadening due to splittings caused by imperfect coherent averaging of MAS. The second strategy is to obtain pure isotropic proton (PIP) spectra in solids, by parametrically mapping any residual broadening due to imperfect averaging into a second dimension of a multidimensional correlation spectrum.
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| first_indexed | 2024-04-09T12:33:13Z |
| format | Article |
| id | doaj.art-0dafe9dc08084ea2b858d88b4d78acf0 |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-04-09T12:33:13Z |
| publishDate | 2023-04-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-0dafe9dc08084ea2b858d88b4d78acf02023-05-16T00:10:58ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242023-04-0177410.2533/chimia.2023.212Improvements in Resolution of 1H NMR of solidsBruno Simões de Almeida0Lyndon Emsley1Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 LausanneInstitut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne Magic angle spinning (MAS) in 1H NMR has allowed progress from featureless spectra in static samples to linewidths of a few hundreds of Hertz for powdered solids at the fastest spinning rates available today (100-150 kHz). While this is a remarkable improvement, this level of resolution is still limiting to the widespread use of 1H NMR for complex systems. This review will discuss two recent alternative strategies that have significantly improved 1H resolution, when combined with fast MAS. The first is based on anti-z-COSY, a 2D experiment originally used for J decoupling in liquids, which removes residual broadening due to splittings caused by imperfect coherent averaging of MAS. The second strategy is to obtain pure isotropic proton (PIP) spectra in solids, by parametrically mapping any residual broadening due to imperfect averaging into a second dimension of a multidimensional correlation spectrum. https://www.chimia.ch/chimia/article/view/6950Magic angle spinning anti-z COSYPIPSolid-state NMR |
| spellingShingle | Bruno Simões de Almeida Lyndon Emsley Improvements in Resolution of 1H NMR of solids CHIMIA Magic angle spinning anti-z COSY PIP Solid-state NMR |
| title | Improvements in Resolution of 1H NMR of solids |
| title_full | Improvements in Resolution of 1H NMR of solids |
| title_fullStr | Improvements in Resolution of 1H NMR of solids |
| title_full_unstemmed | Improvements in Resolution of 1H NMR of solids |
| title_short | Improvements in Resolution of 1H NMR of solids |
| title_sort | improvements in resolution of 1h nmr of solids |
| topic | Magic angle spinning anti-z COSY PIP Solid-state NMR |
| url | https://www.chimia.ch/chimia/article/view/6950 |
| work_keys_str_mv | AT brunosimoesdealmeida improvementsinresolutionof1hnmrofsolids AT lyndonemsley improvementsinresolutionof1hnmrofsolids |