Atopic dermatitis
<p>Abstract</p> <p>Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life of affected individuals as well as their families. Although the pathogenesis of the disorder is not completely understood, it appears to result from the co...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-11-01
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| Series: | Allergy, Asthma & Clinical Immunology |
| Online Access: | http://www.aacijournal.com/content/7/S1/S4 |
| _version_ | 1818147040947863552 |
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| author | Watson Wade Kapur Sandeep |
| author_facet | Watson Wade Kapur Sandeep |
| author_sort | Watson Wade |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life of affected individuals as well as their families. Although the pathogenesis of the disorder is not completely understood, it appears to result from the complex interplay between defects in skin barrier function, environmental and infectious agents, and immune abnormalities. There are no specific diagnostic tests for AD; therefore, the diagnosis is based on specific clinical criteria that take into account the patient’s history and clinical manifestations. Successful management of the disorder requires a multifaceted approach that involves education, optimal skin care practices, anti-inflammatory treatment with topical corticosteroids and/or topical calcineurin inhibitors (TCIs), the use of first-generation antihistamines to help manage sleep disturbances, and the treatment of skin infections. Systemic corticosteroids may also be used, but are generally reserved for the acute treatment of severe flare-ups. Topical corticosteroids are the first-line pharmacologic treatments for AD, and evidence suggests that these agents may also be beneficial for the prophylaxis of disease flare-ups. Although the prognosis for patients with AD is generally favourable, those patients with severe, widespread disease and concomitant atopic conditions, such as asthma and allergic rhinitis, are likely to experience poorer outcomes.</p> |
| first_indexed | 2024-12-11T12:28:56Z |
| format | Article |
| id | doaj.art-0db6a94b36af40a59e630a33c73831b2 |
| institution | Directory Open Access Journal |
| issn | 1710-1484 1710-1492 |
| language | English |
| last_indexed | 2024-12-11T12:28:56Z |
| publishDate | 2011-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Allergy, Asthma & Clinical Immunology |
| spelling | doaj.art-0db6a94b36af40a59e630a33c73831b22022-12-22T01:07:17ZengBMCAllergy, Asthma & Clinical Immunology1710-14841710-14922011-11-017Suppl 1S410.1186/1710-1492-7-S1-S4Atopic dermatitisWatson WadeKapur Sandeep<p>Abstract</p> <p>Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life of affected individuals as well as their families. Although the pathogenesis of the disorder is not completely understood, it appears to result from the complex interplay between defects in skin barrier function, environmental and infectious agents, and immune abnormalities. There are no specific diagnostic tests for AD; therefore, the diagnosis is based on specific clinical criteria that take into account the patient’s history and clinical manifestations. Successful management of the disorder requires a multifaceted approach that involves education, optimal skin care practices, anti-inflammatory treatment with topical corticosteroids and/or topical calcineurin inhibitors (TCIs), the use of first-generation antihistamines to help manage sleep disturbances, and the treatment of skin infections. Systemic corticosteroids may also be used, but are generally reserved for the acute treatment of severe flare-ups. Topical corticosteroids are the first-line pharmacologic treatments for AD, and evidence suggests that these agents may also be beneficial for the prophylaxis of disease flare-ups. Although the prognosis for patients with AD is generally favourable, those patients with severe, widespread disease and concomitant atopic conditions, such as asthma and allergic rhinitis, are likely to experience poorer outcomes.</p>http://www.aacijournal.com/content/7/S1/S4 |
| spellingShingle | Watson Wade Kapur Sandeep Atopic dermatitis Allergy, Asthma & Clinical Immunology |
| title | Atopic dermatitis |
| title_full | Atopic dermatitis |
| title_fullStr | Atopic dermatitis |
| title_full_unstemmed | Atopic dermatitis |
| title_short | Atopic dermatitis |
| title_sort | atopic dermatitis |
| url | http://www.aacijournal.com/content/7/S1/S4 |
| work_keys_str_mv | AT watsonwade atopicdermatitis AT kapursandeep atopicdermatitis |