Bioinspired Membrane-Coated Nanoplatform for Targeted Tumor Immunotherapy

Immunotherapy can effectively activate the immune system and reshape the tumor immune microenvironment, which has been an alternative method in cancer therapy besides surgery, radiotherapy, and chemotherapy. However, the current clinical outcomes are not satisfied due to the lack of targeting of the...

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Main Authors: Dan Mu, Pan He, Yesi Shi, Lai Jiang, Gang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.819817/full
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author Dan Mu
Pan He
Yesi Shi
Lai Jiang
Gang Liu
author_facet Dan Mu
Pan He
Yesi Shi
Lai Jiang
Gang Liu
author_sort Dan Mu
collection DOAJ
description Immunotherapy can effectively activate the immune system and reshape the tumor immune microenvironment, which has been an alternative method in cancer therapy besides surgery, radiotherapy, and chemotherapy. However, the current clinical outcomes are not satisfied due to the lack of targeting of the treatment with some unexpected damages to the human body. Recently, cell membrane-based bioinspired nanoparticles for tumor immunotherapy have attracted much attention because of their superior immune regulating, drug delivery, excellent tumor targeting, and biocompatibility. Together, the article reviews the recent progress of cell membrane-based bioinspired nanoparticles for immunotherapy in cancer treatment. We also evaluate the prospect of bioinspired nanoparticles in immunotherapy for cancer. This strategy may open up new research directions for cancer therapy.
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spelling doaj.art-0db917d89f394f6daa662d98a961f0252022-12-21T17:49:25ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-01-011110.3389/fonc.2021.819817819817Bioinspired Membrane-Coated Nanoplatform for Targeted Tumor ImmunotherapyDan MuPan HeYesi ShiLai JiangGang LiuImmunotherapy can effectively activate the immune system and reshape the tumor immune microenvironment, which has been an alternative method in cancer therapy besides surgery, radiotherapy, and chemotherapy. However, the current clinical outcomes are not satisfied due to the lack of targeting of the treatment with some unexpected damages to the human body. Recently, cell membrane-based bioinspired nanoparticles for tumor immunotherapy have attracted much attention because of their superior immune regulating, drug delivery, excellent tumor targeting, and biocompatibility. Together, the article reviews the recent progress of cell membrane-based bioinspired nanoparticles for immunotherapy in cancer treatment. We also evaluate the prospect of bioinspired nanoparticles in immunotherapy for cancer. This strategy may open up new research directions for cancer therapy.https://www.frontiersin.org/articles/10.3389/fonc.2021.819817/fullbioinspired membranenanoparticletumor targetingimmunotherapynanobiotechnology applications
spellingShingle Dan Mu
Pan He
Yesi Shi
Lai Jiang
Gang Liu
Bioinspired Membrane-Coated Nanoplatform for Targeted Tumor Immunotherapy
Frontiers in Oncology
bioinspired membrane
nanoparticle
tumor targeting
immunotherapy
nanobiotechnology applications
title Bioinspired Membrane-Coated Nanoplatform for Targeted Tumor Immunotherapy
title_full Bioinspired Membrane-Coated Nanoplatform for Targeted Tumor Immunotherapy
title_fullStr Bioinspired Membrane-Coated Nanoplatform for Targeted Tumor Immunotherapy
title_full_unstemmed Bioinspired Membrane-Coated Nanoplatform for Targeted Tumor Immunotherapy
title_short Bioinspired Membrane-Coated Nanoplatform for Targeted Tumor Immunotherapy
title_sort bioinspired membrane coated nanoplatform for targeted tumor immunotherapy
topic bioinspired membrane
nanoparticle
tumor targeting
immunotherapy
nanobiotechnology applications
url https://www.frontiersin.org/articles/10.3389/fonc.2021.819817/full
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AT panhe bioinspiredmembranecoatednanoplatformfortargetedtumorimmunotherapy
AT yesishi bioinspiredmembranecoatednanoplatformfortargetedtumorimmunotherapy
AT laijiang bioinspiredmembranecoatednanoplatformfortargetedtumorimmunotherapy
AT gangliu bioinspiredmembranecoatednanoplatformfortargetedtumorimmunotherapy