Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema
COPD is a highly prevalent, chronic and irreversible obstructive airway disease without curative treatment. Standard therapeutic strategies, both non-pharmacological and pharmacological, have only limited effects on lung function parameters of patients with severe disease. Despite optimal pharmacolo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2023-12-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/32/170/230004.full |
| _version_ | 1797368430732509184 |
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| author | Stephanie Everaerts Christelle M. Vandervelde Pallav Shah Dirk-Jan Slebos Laurens J. Ceulemans |
| author_facet | Stephanie Everaerts Christelle M. Vandervelde Pallav Shah Dirk-Jan Slebos Laurens J. Ceulemans |
| author_sort | Stephanie Everaerts |
| collection | DOAJ |
| description | COPD is a highly prevalent, chronic and irreversible obstructive airway disease without curative treatment. Standard therapeutic strategies, both non-pharmacological and pharmacological, have only limited effects on lung function parameters of patients with severe disease. Despite optimal pharmacological treatment, many patients with severe COPD still have a high burden of dyspnoea and a poor quality of life. If these patients have severe lung emphysema, with hyperinflation as the driver of symptoms and exercise intolerance, lung volume reduction may be an effective treatment with a significant impact on lung function, exercise capacity and quality of life. Currently, different lung volume reduction approaches, both surgical and bronchoscopic, have shown encouraging results and have been implemented in COPD treatment recommendations. Nevertheless, choosing the optimal lung volume reduction strategy for an individual patient remains challenging. Moreover, there is still room for improving durability of effect and safety in all available procedures. Ongoing and innovative research is essential to push this field forwards. This review provides an overview of results and limitations of the current lung volume reduction options for patients with severe lung emphysema and hyperinflation. |
| first_indexed | 2024-03-08T17:32:21Z |
| format | Article |
| id | doaj.art-0db91d5d30914c70b21d4c3bf4276dd1 |
| institution | Directory Open Access Journal |
| issn | 0905-9180 1600-0617 |
| language | English |
| last_indexed | 2024-03-08T17:32:21Z |
| publishDate | 2023-12-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj.art-0db91d5d30914c70b21d4c3bf4276dd12024-01-02T14:19:48ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172023-12-013217010.1183/16000617.0004-20230004-2023Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysemaStephanie Everaerts0Christelle M. Vandervelde1Pallav Shah2Dirk-Jan Slebos3Laurens J. Ceulemans4 Department of Pulmonary Diseases, University Hospitals Leuven, Leuven, Belgium Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium Department of Pulmonology, Royal Brompton Hospital, London, UK Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium COPD is a highly prevalent, chronic and irreversible obstructive airway disease without curative treatment. Standard therapeutic strategies, both non-pharmacological and pharmacological, have only limited effects on lung function parameters of patients with severe disease. Despite optimal pharmacological treatment, many patients with severe COPD still have a high burden of dyspnoea and a poor quality of life. If these patients have severe lung emphysema, with hyperinflation as the driver of symptoms and exercise intolerance, lung volume reduction may be an effective treatment with a significant impact on lung function, exercise capacity and quality of life. Currently, different lung volume reduction approaches, both surgical and bronchoscopic, have shown encouraging results and have been implemented in COPD treatment recommendations. Nevertheless, choosing the optimal lung volume reduction strategy for an individual patient remains challenging. Moreover, there is still room for improving durability of effect and safety in all available procedures. Ongoing and innovative research is essential to push this field forwards. This review provides an overview of results and limitations of the current lung volume reduction options for patients with severe lung emphysema and hyperinflation.http://err.ersjournals.com/content/32/170/230004.full |
| spellingShingle | Stephanie Everaerts Christelle M. Vandervelde Pallav Shah Dirk-Jan Slebos Laurens J. Ceulemans Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema European Respiratory Review |
| title | Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema |
| title_full | Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema |
| title_fullStr | Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema |
| title_full_unstemmed | Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema |
| title_short | Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema |
| title_sort | surgical and bronchoscopic pulmonary function improving procedures in lung emphysema |
| url | http://err.ersjournals.com/content/32/170/230004.full |
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