Deep Crypt Secretory Cell Differentiation in the Colonic Epithelium Is Regulated by Sprouty2 and Interleukin 13Summary

Deep Crypt Secretory Cell Differentiation in the Colonic Epithelium Is Regulated by Sprouty2 and Interleukin 13Summary

Background & Aims: Deep crypt secretory (DCS) cells are a critical component of the colonic stem cell niche. However, the regulatory mechanisms controlling DCS cell numbers and function are not well understood. Sprouty2 is an inflammation-responsive regulator of intracellular signaling that...

Full description

Bibliographic Details
Main Authors: Michael A. Schumacher, Cambrian Y. Liu, Kay Katada, Megan H. Thai, Jonathan J. Hsieh, Britany J. Hansten, Amanda Waddell, Michael J. Rosen, Mark R. Frey
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
IL13
ILC2
Deep Crypt Secretory Cell
RELMβ
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22002375

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X22002375

Similar Items