From Batch to the Semi-Continuous Flow Hydrogenation of <i>p</i>NB, <i>p</i>NZ-Protected Meropenem

Meropenem is currently the most common carbapenem in clinical applications. Industrially, the final synthetic step is characterized by a heterogeneous catalytic hydrogenation in batch mode with hydrogen and Pd/C. The required high-quality standard is very difficult to meet and specific conditions ar...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Marziale Comito, Riccardo Monguzzi, Silvia Tagliapietra, Angelo Maspero, Giovanni Palmisano, Giancarlo Cravotto
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: MDPI AG 2023-04-01
Σειρά:Pharmaceutics
Θέματα:
Διαθέσιμο Online:https://www.mdpi.com/1999-4923/15/5/1322