Evaluation of the Antioxidant, Antidiabetic, and Antiplasmodial Activities of Xanthones Isolated from <i>Garcinia forbesii</i> and Their <i>In Silico</i> Studies

Evaluation of the Antioxidant, Antidiabetic, and Antiplasmodial Activities of Xanthones Isolated from <i>Garcinia forbesii</i> and Their <i>In Silico</i> Studies

This study aimed to isolate xanthones from <i>Garcinia forbesii</i> and evaluated their activity in vitro and <i>in silico</i>. The isolated compounds were evaluated for their antioxidant activity by DPPH, ABTS and FRAP methods. The antidiabetic activity was performed against...

Full description

Bibliographic Details
Main Authors:	Johanis Wairata, Edwin Risky Sukandar, Arif Fadlan, Adi Setyo Purnomo, Muhammad Taher, Taslim Ersam
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Series:	Biomedicines
Subjects:	<i>Garcinia forbesii</i> xanthones antioxidant antidiabetic antiplasmodial molecular docking
Online Access:	https://www.mdpi.com/2227-9059/9/10/1380

Similar Items

Total phenolic and flavonoid contents, antioxidant, antidiabetic and antiplasmodial activities of Garcinia forbesii King: A correlation study
by: Johanis Wairata, et al.
Published: (2022-02-01)

Cytotoxic and Anti-Inflammatory Activities of Dihydroisocoumarin and Xanthone Derivatives from <i>Garcinia picrorhiza</i>
by: Edwin R. Sukandar, et al.
Published: (2021-11-01)

Garcinia dulcis and Garcinia forbesii King fruit peel extract: Secondary metabolite composition, antioxidant, and elastase inhibitory activity evaluation
by: Neneng Siti Silfi Ambarwati, et al.
Published: (2024-01-01)

Biological Activity Evaluation and In Silico Studies of Polyprenylated Benzophenones from <i>Garcinia celebica</i>
by: Yenni Pintauli Pasaribu, et al.
Published: (2021-11-01)

AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL, METANOL, DAN AQUADES DARI KULIT BUAH MUNDAR (Garcinia forbesii)
by: Muhammad Ikhwan Rizki, et al.
Published: (2022-10-01)

AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL, METANOL, DAN AQUADES DARI KULIT BUAH MUNDAR (Garcinia forbesii)
by: Muhammad Ikhwan Rizki, et al.
Published: (2022-10-01)

In vitro and In vivo Antiplasmodial of Stem Bark Extract of Garcinia husor
by: Healthy Kainama, et al.
Published: (2019-10-01)

5,5′-Oxybis(1,3,7-trihydroxy-9<i>H</i>-xanthen-9-one): A New Xanthone from the Stem Bark of <i>Garcinia porrecta</i> (Clusiaceae)
by: Ayu N. Safitri, et al.
Published: (2020-08-01)

In-vitro studies on antioxidant and antidiabetic potential of Sesoot (Garcinia picrorrhiza Miq.) fruit ethanolic extract from Indonesia
by: Sri Utami, et al.
Published: (2021-07-01)

Antidiabetic properties of garciniacowone L, a new xanthone with an unusual 5,5,8a-trimethyloctahydro-2H-1-benzopyran moiety, and other xanthones from the twig extract of Garcinia cowa Roxb. ex Choisy
by: Rawiwan Charoensup, et al.
Published: (2022-08-01)

POTENSI DARI EKSTRAK DAN FRAKSI KULIT BUAH MUNDAR (Garcinia forbesii) SEBAGAI TABIR SURYA BERDASARKAN NILAI SUN PROTECTION FACTOR (SPF)
by: Muhammad Ikhwan Rizki, et al.
Published: (2021-10-01)

POTENSI DARI EKSTRAK DAN FRAKSI KULIT BUAH MUNDAR (Garcinia forbesii) SEBAGAI TABIR SURYA BERDASARKAN NILAI SUN PROTECTION FACTOR (SPF)
by: Muhammad Ikhwan Rizki, et al.
Published: (2021-10-01)

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana
by: Zeng Xu, et al.
Published: (2014-02-01)

Xanthones from the Pericarp of Garcinia mangostana
by: Renyue Yang, et al.
Published: (2017-04-01)

Multitarget Action of Xanthones from <i>Garcinia mangostana</i> against α-Amylase, α-Glucosidase and Pancreatic Lipase
by: Juan Cardozo-Muñoz, et al.
Published: (2022-05-01)

A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds
by: Françoise Guéritte, et al.
Published: (2010-10-01)

Potency of Xanthone Derivatives from <i>Garcinia mangostana</i> L. for COVID-19 Treatment through Angiotensin-Converting Enzyme 2 and Main Protease Blockade: A Computational Study
by: Cecep Suhandi, et al.
Published: (2023-07-01)

Demethylcalabaxanthone from <i>Garcinia mangostana</i> Exerts Antioxidant Effects through the Activation of the Nrf2 Pathway as Assessed via Molecular Docking and Biological Evaluation
by: Simona De Vita, et al.
Published: (2023-11-01)

Phytochemical, Antimicrobial and Antiprotozoal Evaluation of Garcinia Mangostana Pericarp and α-Mangostin, Its Major Xanthone Derivative
by: Louis Maes, et al.
Published: (2013-09-01)

Prenylated Xanthones from the Bark of Garcinia xanthochymus and Their 1,1-Diphenyl-2-picrylhydrazyl (DPPH) Radical Scavenging Activities
by: Hong-wu He, et al.
Published: (2010-10-01)

Brine shrimp cytotoxicity potential of alpha-mangostin and dulxanthone D from Garcinia mangostana
by: Kandasamy Sasikumar, et al.
Published: (2019-07-01)

Komponen kimia daripada Garcinia Forbesii King /
by: 370640 Sivabalan Velayutham
Published: (1996)

Xanthones from the Leaves of Garcinia cowa Induce Cell Cycle Arrest, Apoptosis, and Autophagy in Cancer Cells
by: Zhengxiang Xia, et al.
Published: (2015-06-01)

Chemical constituents and biological activities of Garcinia cowa Roxb.
by: Thunwadee Ritthiwigrom
Published: (2013-06-01)

Garcixanthone E and Garcimangophenone C: New Metabolites from <i>Garcinia mangostana</i> and Their Cytotoxic and Alpha Amylase Inhibitory Potential
by: Gamal A. Mohamed, et al.
Published: (2022-11-01)

Biological properties in relation to health promotion effects of Garcinia mangostana (queen of fruit)
by: Naymul Karim, et al.
Published: (2018-09-01)

In Vitro and In Vivo Antiangiogenic Activity of Caged Polyprenylated Xanthones Isolated from Garcinia hanburyi Hook. f.
by: Jianhong Yang, et al.
Published: (2013-12-01)

Renoprotective Effects of Xanthone Derivatives from Garcinia mangostana Against High Fat Diet and Streptozotocin-Induced Type II Diabetes in Mice
by: Naymul KARIM, et al.
Published: (2016-12-01)

Effects of the Bark Resin Extract of <i>Garcinia nigrolineata</i> on Chronic Stress-Induced Memory Deficit in Mice Model and the In Vitro Monoamine Oxidases and β-Amyloid Aggregation Inhibitory Activities of Its Prenylated Xanthone Constituents
by: Charinya Khamphukdee, et al.
Published: (2022-05-01)

Lectotypifications of Three Names in <i>Garcinia</i>, Synonymy of <i>Garcinia pedunculata</i> and Detailed Descriptions of Three Species in <i>Garcinia</i> Section <i>Brindonia</i> (Clusiaceae)
by: Chatchai Ngernsaengsaruay
Published: (2022-07-01)

Anti-Tumor Xanthones from Garcinia nujiangensis Suppress Proliferation, and Induce Apoptosis via PARP, PI3K/AKT/mTOR, and MAPK/ERK Signaling Pathways in Human Ovarian Cancers Cells
by: Tang Z, et al.
Published: (2020-09-01)

Mangostanin, a Xanthone Derived from <i>Garcinia mangostana</i> Fruit, Exerts Protective and Reparative Effects on Oxidative Damage in Human Keratinocytes
by: Mario Abate, et al.
Published: (2022-01-01)

Plastomes of <i>Garcinia mangostana</i> L. and Comparative Analysis with Other <i>Garcinia</i> Species
by: Ching-Ching Wee, et al.
Published: (2023-02-01)

<i>Garcinia mangostana</i> L. Pericarp Extract and Its Active Compound α-Mangostin as Potential Inhibitors of Immune Checkpoint Programmed Death Ligand-1
by: Sandar Naing, et al.
Published: (2023-10-01)

Xanthones from garcinia eugenifolia / M.Taher, Muhammad Sum Idris, Dayar Arbain
by: 174651 M. Taher, et al.

Characterization of Nanocellulose Obtained from Cereus Forbesii (a South American cactus)
by: Camilo Orrabalis, et al.
Published: (2020-01-01)

Cytotoxic Isobractatin (Prenylated Xanthone) Epimer Mixture of <i>Garcinia eugenifolia</i>
by: Sri Hartati, et al.
Published: (2014-10-01)

Antibacterial and EGFR-Tyrosine Kinase Inhibitory Activities of Polyhydroxylated Xanthones from Garcinia succifolia
by: Susawat Duangsrisai, et al.
Published: (2014-11-01)

Triterpene Derivatives from <i>Garcinia oligantha</i> and Their Anti-Cancer Activity
by: Xiaohui Peng, et al.
Published: (2023-01-01)

Constituents of the Stem Bark of <i>Trichilia monadelpha</i> (Thonn.) J. J. De Wilde (Meliaceae) and Their Antibacterial and Antiplasmodial Activities
by: Arnauld Kenfack Djoumessi, et al.
Published: (2023-02-01)