Microwave-assisted synthesis of biologically active amide derivatives of naphthenic acids under neat conditions

Within the field of green chemistry, a noticeable results were obtained in the solvent-free synthesis of amide derivatives of naphthenic acids under microwave irradiation. Naphthenic acid amides, anilides, and morpholides were synthesized directly from free carboxylic acids and amines in the absence...

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Bibliographic Details
Main Authors: Ljubica Grbović, Bojana Radovan Vasiljević, Ksenija Pavlović, Timea Hajnal-Jafari, Simonida Đurić, Mirjana Popsavin, Slavko Kevrešan
Format: Article
Language:English
Published: Society of Chemists and Technologists of Macedonia 2018-06-01
Series:Macedonian Journal of Chemistry and Chemical Engineering
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Online Access:https://mjcce.org.mk/index.php/MJCCE/article/view/1371
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Summary:Within the field of green chemistry, a noticeable results were obtained in the solvent-free synthesis of amide derivatives of naphthenic acids under microwave irradiation. Naphthenic acid amides, anilides, and morpholides were synthesized directly from free carboxylic acids and amines in the absence of solvent and catalyst under high-temperature heating in a closed-vessel system of microwave reactor. With this new and efficient method, different primary, secondary, and tertiary amide derivatives of naphthenic acids were obtained in good to excellent yields. Synthesized derivatives were assayed as plant rooting agents for their stimulative effects on the formation of adventitious roots in sunflower cuttings and susceptibility for growth stimulation of Pseudomonas sp. strains.
ISSN:1857-5552
1857-5625