Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell Imaging
A new fluorescent probe P based on rhodamine for Cu2+ was synthesized and characterized. The new probe P showed high selectivity to Cu2+ over other tested metal ions. With optimal conditions, the proposed probe P worked in a wide linear range of 1.0 × 10−6–1.0 × 10−5 M with a detection limit of 3.3...
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-11-01
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| Series: | Sensors |
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| Online Access: | http://www.mdpi.com/1424-8220/14/11/21375 |
| _version_ | 1811213323857821696 |
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| author | Chunwei Yu Yingying Wen Jun Zhang |
| author_facet | Chunwei Yu Yingying Wen Jun Zhang |
| author_sort | Chunwei Yu |
| collection | DOAJ |
| description | A new fluorescent probe P based on rhodamine for Cu2+ was synthesized and characterized. The new probe P showed high selectivity to Cu2+ over other tested metal ions. With optimal conditions, the proposed probe P worked in a wide linear range of 1.0 × 10−6–1.0 × 10−5 M with a detection limit of 3.3 × 10−7 M Cu2+ in ethanol-water solution (9:1, v:v, 20 mM HEPES, pH 7.0). Furthermore, it has been used for imaging of Cu2+ in living cells with satisfying results. |
| first_indexed | 2024-04-12T05:43:49Z |
| format | Article |
| id | doaj.art-0dbddccee295459ab565fe713121be5d |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-12T05:43:49Z |
| publishDate | 2014-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-0dbddccee295459ab565fe713121be5d2022-12-22T03:45:30ZengMDPI AGSensors1424-82202014-11-011411213752138410.3390/s141121375s141121375Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell ImagingChunwei Yu0Yingying Wen1Jun Zhang2Laboratory of Environmental Monitoring, School of Tropical and Laboratory Medicine, Hainan Medical University, Haikou 571199, ChinaLaboratory of Environmental Monitoring, School of Tropical and Laboratory Medicine, Hainan Medical University, Haikou 571199, ChinaLaboratory of Environmental Monitoring, School of Tropical and Laboratory Medicine, Hainan Medical University, Haikou 571199, ChinaA new fluorescent probe P based on rhodamine for Cu2+ was synthesized and characterized. The new probe P showed high selectivity to Cu2+ over other tested metal ions. With optimal conditions, the proposed probe P worked in a wide linear range of 1.0 × 10−6–1.0 × 10−5 M with a detection limit of 3.3 × 10−7 M Cu2+ in ethanol-water solution (9:1, v:v, 20 mM HEPES, pH 7.0). Furthermore, it has been used for imaging of Cu2+ in living cells with satisfying results.http://www.mdpi.com/1424-8220/14/11/21375rhodamine derivativefluorescence enhancementfluorescence imaging |
| spellingShingle | Chunwei Yu Yingying Wen Jun Zhang Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell Imaging Sensors rhodamine derivative fluorescence enhancement fluorescence imaging |
| title | Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell Imaging |
| title_full | Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell Imaging |
| title_fullStr | Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell Imaging |
| title_full_unstemmed | Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell Imaging |
| title_short | Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell Imaging |
| title_sort | synthesis of a cu2 selective probe derived from rhodamine and its application in cell imaging |
| topic | rhodamine derivative fluorescence enhancement fluorescence imaging |
| url | http://www.mdpi.com/1424-8220/14/11/21375 |
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