Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents
A key difficulty to overcome in pyridinium salts functionalization is the regioselectivity at the two competing C2 and C4 sites. Here, the authors show bifunctional N-aminopyridinium salts reagents delivering both the aminyl radical and the pyridyl group to an olefin with C4-pyridyl regioselectivity...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-12216-3 |
| _version_ | 1818991326766563328 |
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| author | Yonghoon Moon Bohyun Park Inwon Kim Gyumin Kang Sanghoon Shin Dahye Kang Mu-Hyun Baik Sungwoo Hong |
| author_facet | Yonghoon Moon Bohyun Park Inwon Kim Gyumin Kang Sanghoon Shin Dahye Kang Mu-Hyun Baik Sungwoo Hong |
| author_sort | Yonghoon Moon |
| collection | DOAJ |
| description | A key difficulty to overcome in pyridinium salts functionalization is the regioselectivity at the two competing C2 and C4 sites. Here, the authors show bifunctional N-aminopyridinium salts reagents delivering both the aminyl radical and the pyridyl group to an olefin with C4-pyridyl regioselectivity. |
| first_indexed | 2024-12-20T20:08:30Z |
| format | Article |
| id | doaj.art-0dbe2b05121842239e7518e52f4af4ba |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T20:08:30Z |
| publishDate | 2019-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-0dbe2b05121842239e7518e52f4af4ba2022-12-21T19:27:53ZengNature PortfolioNature Communications2041-17232019-09-011011910.1038/s41467-019-12216-3Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagentsYonghoon Moon0Bohyun Park1Inwon Kim2Gyumin Kang3Sanghoon Shin4Dahye Kang5Mu-Hyun Baik6Sungwoo Hong7Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)A key difficulty to overcome in pyridinium salts functionalization is the regioselectivity at the two competing C2 and C4 sites. Here, the authors show bifunctional N-aminopyridinium salts reagents delivering both the aminyl radical and the pyridyl group to an olefin with C4-pyridyl regioselectivity.https://doi.org/10.1038/s41467-019-12216-3 |
| spellingShingle | Yonghoon Moon Bohyun Park Inwon Kim Gyumin Kang Sanghoon Shin Dahye Kang Mu-Hyun Baik Sungwoo Hong Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents Nature Communications |
| title | Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents |
| title_full | Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents |
| title_fullStr | Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents |
| title_full_unstemmed | Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents |
| title_short | Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents |
| title_sort | visible light induced alkene aminopyridylation using n aminopyridinium salts as bifunctional reagents |
| url | https://doi.org/10.1038/s41467-019-12216-3 |
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