Porcine parvovirus triggers autophagy through the AMPK/Raptor/mTOR pathway to promote viral replication in porcine placental trophoblasts

Porcine parvovirus triggers autophagy through the AMPK/Raptor/mTOR pathway to promote viral replication in porcine placental trophoblasts

Abstract Autophagy has been demonstrated to play important roles in the infection and pathogenesis of many viruses. We previously found that porcine parvovirus (PPV) infection can induce autophagy in porcine placental trophoblast cells (PTCs), but its underlying mechanism has not yet been fully reve...

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Bibliographic Details
Main Authors: Xiujuan Zhang, Peipei Ma, Ting Shao, Yingli Xiong, Qian Du, Songbiao Chen, Bichen Miao, Xuezhi Zhang, Xiaoya Wang, Yong Huang, Dewen Tong
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Veterinary Research
Subjects:
Porcine parvovirus
placental trophoblast cells
autophagy
signalling pathway
Online Access:https://doi.org/10.1186/s13567-022-01048-7

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