The Context-Dependent Impact of Integrin-Associated CD151 and Other Tetraspanins on Cancer Development and Progression: A Class of Versatile Mediators of Cellular Function and Signaling, Tumorigenesis and Metastasis

The Context-Dependent Impact of Integrin-Associated CD151 and Other Tetraspanins on Cancer Development and Progression: A Class of Versatile Mediators of Cellular Function and Signaling, Tumorigenesis and Metastasis

As a family of integral membrane proteins, tetraspanins have been functionally linked to a wide spectrum of human cancers, ranging from breast, colon, lung, ovarian, prostate, and skin carcinomas to glioblastoma. CD151 is one such prominent member of the tetraspanin family recently suggested to medi...

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Bibliographic Details
Main Authors: Sonia Erfani, Hui Hua, Yueyin Pan, Binhua P. Zhou, Xiuwei H. Yang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
CD151
tetraspanins
breast cancer
Wnt pathway
integrins
cancer stem cells
Online Access:https://www.mdpi.com/2072-6694/13/9/2005

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