Green tea EGCG inhibits naïve CD4+ T cell division and progression in mice: An integration of network pharmacology, molecular docking and experimental validation

Green tea EGCG inhibits naïve CD4+ T cell division and progression in mice: An integration of network pharmacology, molecular docking and experimental validation

Dietary green tea epigallocatechin-3-gallate (EGCG) could attenuate experimental autoimmune encephalomyelitis via the modification of the balance of CD4+ T helper (Th) cells. Moreover, EGCG administration in vitro has a direct impact on the regulatory cytokines and differentiation of CD4+ T cells. H...

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Bibliographic Details
Main Authors: Xinli Niu, Zejin Liu, Junpeng Wang, Dayong Wu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Food Science
Subjects:
EGCG
Network pharmacology
Molecular docking
Cell cycle
T cell-mediated autoimmune diseases
multiple sclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2665927123001053

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