MICAL1 activation by PAK1 mediates actin filament disassembly

MICAL1 activation by PAK1 mediates actin filament disassembly

Summary: The MICAL1 monooxygenase is an important regulator of filamentous actin (F-actin) structures. Although MICAL1 has been shown to be regulated via protein-protein interactions at the autoinhibitory carboxyl terminus, a link between actin-regulatory RHO GTPase signaling pathways and MICAL1 has...

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Bibliographic Details
Main Authors: David J. McGarry, Giovanni Castino, Sergio Lilla, Alexandre Carnet, Loughlin Kelly, Katarina Micovic, Sara Zanivan, Michael F. Olson
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Cell Reports
Subjects:
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722012839

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