Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan
Background and Objectives: The global spread of methicillin resistant Staphylococcus aureus (MRSA) constitutes one of the most serious contemporary challenges to the treatment of hospital-acquired infections. We aimed to screen and assess the antibiotic susceptibility pattern of Staphylococcus aureu...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2015-12-01
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| Series: | Iranian Journal of Microbiology |
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| Online Access: | https://ijm.tums.ac.ir/index.php/ijm/article/view/168 |
| _version_ | 1818407875726278656 |
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| author | Mazhar Salim Al-Zoubi Ibrahim Ali Al-Tayyar Emad Hussein Alaa Al Jabali Salih Khudairatd |
| author_facet | Mazhar Salim Al-Zoubi Ibrahim Ali Al-Tayyar Emad Hussein Alaa Al Jabali Salih Khudairatd |
| author_sort | Mazhar Salim Al-Zoubi |
| collection | DOAJ |
| description | Background and Objectives: The global spread of methicillin resistant Staphylococcus aureus (MRSA) constitutes one of the most serious contemporary challenges to the treatment of hospital-acquired infections. We aimed to screen and assess the antibiotic susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in local hospitals of Northern province in Jordan.
Materials and Methods: Staphylococcus aureus was isolated and identified using standard methods from various clinical specimens of different infected body sites from 358 patients during the period from January 2005 to November 2008.
Results: Our analysis showed that 31.6% of S. aureus infections were MRSA, while 31% were multidrug resistance (MDR) and 42.7% were Oxacillin-resistant (ORSA). Most of these strains were isolated from wound specimens. All isolates were susceptible to vancomycin (100%). They were also susceptible to chloramphenicol, linezolid, nitrofurantoin, rifampicin and teicoplanin (>80%), but showed resistance to erythromycin and penicillin.
Conclusion: Vancomycin was the most effective antimicrobial agent against S. aureus. We recommend regular surveillance of hospital associated infections and monitoring antibiotic sensitivity pattern and strict drug policy for antibiotics used within and outside the hospital environments. |
| first_indexed | 2024-12-14T09:34:47Z |
| format | Article |
| id | doaj.art-0dc816f58eb14dad80da8764f4cff6d1 |
| institution | Directory Open Access Journal |
| issn | 2008-3289 2008-4447 |
| language | English |
| last_indexed | 2024-12-14T09:34:47Z |
| publishDate | 2015-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Microbiology |
| spelling | doaj.art-0dc816f58eb14dad80da8764f4cff6d12022-12-21T23:07:58ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472015-12-0175Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of JordanMazhar Salim Al-Zoubi0Ibrahim Ali Al-Tayyar1Emad Hussein2Alaa Al Jabali3Salih Khudairatd4Biology Deparrment, Yarmouk University, Irbid, Jordan AND Molecular Pathology Department, University of Pisa, Italy.Department of Medical Laboratory Science, Faculty of Engineering & Technology, Brack, Sebha University, Lybia.Department of Biological Sciences Yarmouk University, Irbid, 211-63 Jordan.Department of Biological Sciences Yarmouk University, Irbid, 211-63 Jordan.Hussain Cancer Center, Amman, Jordan.Background and Objectives: The global spread of methicillin resistant Staphylococcus aureus (MRSA) constitutes one of the most serious contemporary challenges to the treatment of hospital-acquired infections. We aimed to screen and assess the antibiotic susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in local hospitals of Northern province in Jordan. Materials and Methods: Staphylococcus aureus was isolated and identified using standard methods from various clinical specimens of different infected body sites from 358 patients during the period from January 2005 to November 2008. Results: Our analysis showed that 31.6% of S. aureus infections were MRSA, while 31% were multidrug resistance (MDR) and 42.7% were Oxacillin-resistant (ORSA). Most of these strains were isolated from wound specimens. All isolates were susceptible to vancomycin (100%). They were also susceptible to chloramphenicol, linezolid, nitrofurantoin, rifampicin and teicoplanin (>80%), but showed resistance to erythromycin and penicillin. Conclusion: Vancomycin was the most effective antimicrobial agent against S. aureus. We recommend regular surveillance of hospital associated infections and monitoring antibiotic sensitivity pattern and strict drug policy for antibiotics used within and outside the hospital environments.https://ijm.tums.ac.ir/index.php/ijm/article/view/168S. aureusMRSAMDRORSAAntibiotic susceptibility |
| spellingShingle | Mazhar Salim Al-Zoubi Ibrahim Ali Al-Tayyar Emad Hussein Alaa Al Jabali Salih Khudairatd Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan Iranian Journal of Microbiology S. aureus MRSA MDR ORSA Antibiotic susceptibility |
| title | Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan |
| title_full | Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan |
| title_fullStr | Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan |
| title_full_unstemmed | Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan |
| title_short | Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan |
| title_sort | antimicrobial susceptibility pattern of staphylococcus aureus isolated from clinical specimens in northern area of jordan |
| topic | S. aureus MRSA MDR ORSA Antibiotic susceptibility |
| url | https://ijm.tums.ac.ir/index.php/ijm/article/view/168 |
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