Contribution of the Transcription Factors Sp1/Sp3 and AP-1 to <i>Clusterin</i> Gene Expression during Corneal Wound Healing of Tissue-Engineered Human Corneas

Contribution of the Transcription Factors Sp1/Sp3 and AP-1 to <i>Clusterin</i> Gene Expression during Corneal Wound Healing of Tissue-Engineered Human Corneas

In order to reduce the need for donor corneas, understanding of corneal wound healing and development of an entirely tissue-engineered human cornea (hTECs) is of prime importance. In this study, we exploited the hTEC to determine how deep wound healing affects the transcriptional pattern of corneal...

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Bibliographic Details
Main Authors: Christelle Gross, Gaëtan Le-Bel, Pascale Desjardins, Manel Benhassine, Lucie Germain, Sylvain L. Guérin
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
<i>clusterin</i>
human cornea
tissue-engineering
3D corneal model
wound healing
transcription factor
Online Access:https://www.mdpi.com/1422-0067/22/22/12426

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