Comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department: A randomized controlled study
ABSTRACTBackground This study aimed to assess the safety and efficacy of analgesia with pericapsular nerve group (PENG) block as an adjuvant to morphine infusion for the management of preoperative pain in patients with proximal femur fractures.Methods This single-blinded, parallel-group, randomized...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Egyptian Journal of Anaesthesia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/11101849.2023.2165888 |
| _version_ | 1797957746394398720 |
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| author | Abdelrhman Alshawadfy Ahmed M. Elewa Mahmoud Ahmed Mewafy Ahmed A. Ellilly |
| author_facet | Abdelrhman Alshawadfy Ahmed M. Elewa Mahmoud Ahmed Mewafy Ahmed A. Ellilly |
| author_sort | Abdelrhman Alshawadfy |
| collection | DOAJ |
| description | ABSTRACTBackground This study aimed to assess the safety and efficacy of analgesia with pericapsular nerve group (PENG) block as an adjuvant to morphine infusion for the management of preoperative pain in patients with proximal femur fractures.Methods This single-blinded, parallel-group, randomized trial enrolled 36 adult patients with proximal femur fractures who were prepared for surgery. The patients were randomly allocated to two groups. In the PENG group, 18 patients received a US-guided PENG block as an adjuvant to patient-controlled morphine analgesia (PCA), while in the PCA group, 18 patients received PCA only. The primary outcome was the total morphine consumption in 24 hours before the surgery. The secondary outcomes included the visual analogue scale (VAS), need for rescue analgesia, total sleep hours, incidence of respiratory depression, hemodynamic stability, and incidence of nausea and vomiting during the first 24 hours post-procedure.Results The PENG block significantly decreased the total dose of morphine, VAS score at one-hour post-procedure, need for rescue analgesia, incidence of respiratory depression and nausea but increased the sleeping hours. Vomiting was comparable in the two groups (p = 0.121). Significantly higher mean arterial pressures from 8 to 20 hours after the block as well as heart rates immediately after the block were observed in the PENG group compared to the PCA group.Conclusion In patients with proximal femur fractures, preoperative PENG block can be used as an adjuvant to morphine infusion for controlling the pain and the total dose of morphine usage. |
| first_indexed | 2024-04-11T00:08:21Z |
| format | Article |
| id | doaj.art-0dcccda0c3784eebbdae420f87b68dcf |
| institution | Directory Open Access Journal |
| issn | 1110-1849 |
| language | English |
| last_indexed | 2024-04-11T00:08:21Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Egyptian Journal of Anaesthesia |
| spelling | doaj.art-0dcccda0c3784eebbdae420f87b68dcf2023-01-09T07:47:21ZengTaylor & Francis GroupEgyptian Journal of Anaesthesia1110-18492023-12-01391263110.1080/11101849.2023.2165888Comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department: A randomized controlled studyAbdelrhman Alshawadfy0Ahmed M. Elewa1Mahmoud Ahmed Mewafy2Ahmed A. Ellilly3Department of Anesthesia and Intensive Care, Faculty of Medicine, Suez Canal University, Ismailia, EgyptDepartment of Anesthesia and Intensive Care, Faculty of Medicine, Suez Canal University, Ismailia, EgyptDepartment of Anesthesia and Intensive Care, Faculty of Medicine, Suez Canal University, Ismailia, EgyptDepartment of Anesthesia and Intensive Care, Faculty of Medicine, Suez Canal University, Ismailia, EgyptABSTRACTBackground This study aimed to assess the safety and efficacy of analgesia with pericapsular nerve group (PENG) block as an adjuvant to morphine infusion for the management of preoperative pain in patients with proximal femur fractures.Methods This single-blinded, parallel-group, randomized trial enrolled 36 adult patients with proximal femur fractures who were prepared for surgery. The patients were randomly allocated to two groups. In the PENG group, 18 patients received a US-guided PENG block as an adjuvant to patient-controlled morphine analgesia (PCA), while in the PCA group, 18 patients received PCA only. The primary outcome was the total morphine consumption in 24 hours before the surgery. The secondary outcomes included the visual analogue scale (VAS), need for rescue analgesia, total sleep hours, incidence of respiratory depression, hemodynamic stability, and incidence of nausea and vomiting during the first 24 hours post-procedure.Results The PENG block significantly decreased the total dose of morphine, VAS score at one-hour post-procedure, need for rescue analgesia, incidence of respiratory depression and nausea but increased the sleeping hours. Vomiting was comparable in the two groups (p = 0.121). Significantly higher mean arterial pressures from 8 to 20 hours after the block as well as heart rates immediately after the block were observed in the PENG group compared to the PCA group.Conclusion In patients with proximal femur fractures, preoperative PENG block can be used as an adjuvant to morphine infusion for controlling the pain and the total dose of morphine usage.https://www.tandfonline.com/doi/10.1080/11101849.2023.2165888Analgesiamorphinepericapsular nerve group blockproximal femur fracture |
| spellingShingle | Abdelrhman Alshawadfy Ahmed M. Elewa Mahmoud Ahmed Mewafy Ahmed A. Ellilly Comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department: A randomized controlled study Egyptian Journal of Anaesthesia Analgesia morphine pericapsular nerve group block proximal femur fracture |
| title | Comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department: A randomized controlled study |
| title_full | Comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department: A randomized controlled study |
| title_fullStr | Comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department: A randomized controlled study |
| title_full_unstemmed | Comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department: A randomized controlled study |
| title_short | Comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department: A randomized controlled study |
| title_sort | comparison between pericapsular nerve group block and morphine infusion in reducing pain of proximal femur fracture in the emergency department a randomized controlled study |
| topic | Analgesia morphine pericapsular nerve group block proximal femur fracture |
| url | https://www.tandfonline.com/doi/10.1080/11101849.2023.2165888 |
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