Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
ABSTRACT ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathog...
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| Format: | Article |
| Language: | English |
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Elsevier
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| Series: | Revista Brasileira de Hematologia e Hemoterapia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842016000400331&lng=en&tlng=en |
| _version_ | 1818521376491831296 |
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| author | Luiz Carlos de Mattos |
| author_facet | Luiz Carlos de Mattos |
| author_sort | Luiz Carlos de Mattos |
| collection | DOAJ |
| description | ABSTRACT ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowledge of some structural variability of these carbohydrate antigens and their polymorphic levels of expression in tissue and exocrine secretions, little is known about their biological importance and potential applications in medicine. This review highlights the structural diversity, the biological importance and potential applications of ABO, H, Lewis and secretor histo-blood carbohydrates. |
| first_indexed | 2024-12-11T01:50:12Z |
| format | Article |
| id | doaj.art-0dce019262a244faa527a80b38ef8960 |
| institution | Directory Open Access Journal |
| issn | 1806-0870 |
| language | English |
| last_indexed | 2024-12-11T01:50:12Z |
| publisher | Elsevier |
| record_format | Article |
| series | Revista Brasileira de Hematologia e Hemoterapia |
| spelling | doaj.art-0dce019262a244faa527a80b38ef89602022-12-22T01:24:46ZengElsevierRevista Brasileira de Hematologia e Hemoterapia1806-087038433134010.1016/j.bjhh.2016.07.005S1516-84842016000400331Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydratesLuiz Carlos de MattosABSTRACT ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowledge of some structural variability of these carbohydrate antigens and their polymorphic levels of expression in tissue and exocrine secretions, little is known about their biological importance and potential applications in medicine. This review highlights the structural diversity, the biological importance and potential applications of ABO, H, Lewis and secretor histo-blood carbohydrates.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842016000400331&lng=en&tlng=enHisto-blood groupsABO systemLewis systemCarbohydrate antigenGlycosyltransferases |
| spellingShingle | Luiz Carlos de Mattos Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates Revista Brasileira de Hematologia e Hemoterapia Histo-blood groups ABO system Lewis system Carbohydrate antigen Glycosyltransferases |
| title | Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates |
| title_full | Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates |
| title_fullStr | Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates |
| title_full_unstemmed | Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates |
| title_short | Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates |
| title_sort | structural diversity and biological importance of abo h lewis and secretor histo blood group carbohydrates |
| topic | Histo-blood groups ABO system Lewis system Carbohydrate antigen Glycosyltransferases |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842016000400331&lng=en&tlng=en |
| work_keys_str_mv | AT luizcarlosdemattos structuraldiversityandbiologicalimportanceofabohlewisandsecretorhistobloodgroupcarbohydrates |