Synergistic antimicrobial potential: Exploring the efficacy of poly methacrylic acid (PMAA) polymers, CuO NPs, and pomegranate peel extract against bacterial pathogens

The use of agricultural and biomass waste to treat pollutants is a fruitful sector as it resolves a major problem by a low-cost and eco-friendly source. This study investigates the antimicrobial potential of Pomegranate (P. granatum) peel extract and Copper Oxide (CuO) nanoparticles (NPs), evaluatin...

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Bibliographic Details
Main Authors: Hamsa Thamer, Hanan Ibraheem, Raghda Alsayed, Raghda Makia, Mohammed Kadhom, Husam Salman, Emad Yousif
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624000614
Description
Summary:The use of agricultural and biomass waste to treat pollutants is a fruitful sector as it resolves a major problem by a low-cost and eco-friendly source. This study investigates the antimicrobial potential of Pomegranate (P. granatum) peel extract and Copper Oxide (CuO) nanoparticles (NPs), evaluating their efficacy against various bacterial strains. The P. granatum extract displayed notable bactericidal activity, particularly against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). CuO NPs induced reactive oxygen species, disrupting bacterial mechanisms and altering cellular morphology. Even at lower concentrations, both agents exhibited efficiency comparable to a higher concentration of the pharmaceutical standard (Ciprofloxacin 250 mg/10 ml, 2.5 %). These findings align with previous research, underscoring the antimicrobial properties of P. granatum and the potential of CuO NPs as alternative agents. The study highlights the significance of the ongoing quest for effective and sustainable antimicrobial solutions.
ISSN:2211-7156