A CTGF-YAP Regulatory Pathway Is Essential for Angiogenesis and Barriergenesis in the Retina

A CTGF-YAP Regulatory Pathway Is Essential for Angiogenesis and Barriergenesis in the Retina

Summary: Connective tissue growth factor (CTGF) or cellular communication network 2 (CCN2) is a matricellular protein essential for normal embryonic development and tissue repair. CTGF exhibits cell- and context-dependent activities, but CTGF function in vascular development and barrier function is...

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Bibliographic Details
Main Authors: Sohyun Moon, Sangmi Lee, Joy Ann Caesar, Sarah Pruchenko, Andrew Leask, James A. Knowles, Jose Sinon, Brahim Chaqour
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:iScience
Subjects:
Molecular Biology
Cell Biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220303692

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