Public health initiatives from hospitalized patients with COVID-19, China
Background: Since December 2019, when it first occurred in Wuhan, China, coronavirus disease 2019 (COVID-19) has spread rapidly worldwide via human-to-human transmission. We aimed to describe the epidemiological and demographic features of COVID-19 outside Wuhan. Methods: A single-center case series...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-09-01
|
| Series: | Journal of Infection and Public Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034120305232 |
| _version_ | 1819014714831667200 |
|---|---|
| author | Chenkai Zhao Yueqin Xu Xu Zhang Yaping Zhong Li Long Wenzhi Zhan Tingting Xu Chen Zhan Yuehan Chen Jinghai Zhu Wei Xiao Miao He |
| author_facet | Chenkai Zhao Yueqin Xu Xu Zhang Yaping Zhong Li Long Wenzhi Zhan Tingting Xu Chen Zhan Yuehan Chen Jinghai Zhu Wei Xiao Miao He |
| author_sort | Chenkai Zhao |
| collection | DOAJ |
| description | Background: Since December 2019, when it first occurred in Wuhan, China, coronavirus disease 2019 (COVID-19) has spread rapidly worldwide via human-to-human transmission. We aimed to describe the epidemiological and demographic features of COVID-19 outside Wuhan. Methods: A single-center case series of 136 consecutive (from January 16 to February 17, 2020) patients with confirmed COVID-19 hospitalized in The First People's Hospital of Jingzhou, China, was retrospectively analyzed. Outcomes were followed up until February 19, 2020. Results: Of the 136 patients (median age, 49 years; interquartile range [IQR], 33–63 years; range, 0.3–83 years), 91 (67%) had been to Wuhan or contacted persons from Wuhan. Forty-five (33.1%) were familial clusters. The median incubation period was 6 days (IQR: 4–11 days). All children had an exact exposure history, family members with COVID-19, and “Mild/Moderate” symptoms at admission. Among the 64 elderly patients, 14 (21.9%) had no exposure history, and 43 (67.2%) had a chronic illness. All 11 (8.1%) “Severe/very severe” illness at onset cases and 5 (3.7%) fatal cases were elderly patients. The duration from symptom onset to admission was positively correlated with the duration from symptom onset to endpoint. Overall, patients with a longer incubation period had more severe outcomes. Conclusion: As high-risk susceptible groups, strong protection should be implemented for children and the elderly. Universal screening should be performed for people with a clear exposure history, even lacking apparent symptoms. Given the rapid progression of COVID-19, people should be admitted quickly following symptom onset. |
| first_indexed | 2024-12-21T02:20:14Z |
| format | Article |
| id | doaj.art-0dd2b7e50b794a129f15c2b2df88b68b |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-12-21T02:20:14Z |
| publishDate | 2020-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-0dd2b7e50b794a129f15c2b2df88b68b2022-12-21T19:19:10ZengElsevierJournal of Infection and Public Health1876-03412020-09-0113912291236Public health initiatives from hospitalized patients with COVID-19, ChinaChenkai Zhao0Yueqin Xu1Xu Zhang2Yaping Zhong3Li Long4Wenzhi Zhan5Tingting Xu6Chen Zhan7Yuehan Chen8Jinghai Zhu9Wei Xiao10Miao He11School of Public Health, China Medical University, ChinaThe First People's Hospital of Jingzhou, ChinaThe First People's Hospital of Jingzhou, ChinaSchool of Public Health, China Medical University, ChinaState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, ChinaState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, ChinaState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, ChinaState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, ChinaState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, ChinaSchool of Public Health, China Medical University, ChinaThe First People's Hospital of Jingzhou, China; Corresponding author at: The First People's Hospital of Jingzhou, Jingzhou 434000, Hubei Province, China.School of Public Health, China Medical University, China; Corresponding author at: School of Public Health, China Medical University, Key Laboratory of Environmental Health Damage Research and Assessment, Shenyang 110122, Liaoning Province, China.Background: Since December 2019, when it first occurred in Wuhan, China, coronavirus disease 2019 (COVID-19) has spread rapidly worldwide via human-to-human transmission. We aimed to describe the epidemiological and demographic features of COVID-19 outside Wuhan. Methods: A single-center case series of 136 consecutive (from January 16 to February 17, 2020) patients with confirmed COVID-19 hospitalized in The First People's Hospital of Jingzhou, China, was retrospectively analyzed. Outcomes were followed up until February 19, 2020. Results: Of the 136 patients (median age, 49 years; interquartile range [IQR], 33–63 years; range, 0.3–83 years), 91 (67%) had been to Wuhan or contacted persons from Wuhan. Forty-five (33.1%) were familial clusters. The median incubation period was 6 days (IQR: 4–11 days). All children had an exact exposure history, family members with COVID-19, and “Mild/Moderate” symptoms at admission. Among the 64 elderly patients, 14 (21.9%) had no exposure history, and 43 (67.2%) had a chronic illness. All 11 (8.1%) “Severe/very severe” illness at onset cases and 5 (3.7%) fatal cases were elderly patients. The duration from symptom onset to admission was positively correlated with the duration from symptom onset to endpoint. Overall, patients with a longer incubation period had more severe outcomes. Conclusion: As high-risk susceptible groups, strong protection should be implemented for children and the elderly. Universal screening should be performed for people with a clear exposure history, even lacking apparent symptoms. Given the rapid progression of COVID-19, people should be admitted quickly following symptom onset.http://www.sciencedirect.com/science/article/pii/S1876034120305232Coronavirus disease 2019EpidemiologyIncubation periodHigh-risk susceptible peopleChina |
| spellingShingle | Chenkai Zhao Yueqin Xu Xu Zhang Yaping Zhong Li Long Wenzhi Zhan Tingting Xu Chen Zhan Yuehan Chen Jinghai Zhu Wei Xiao Miao He Public health initiatives from hospitalized patients with COVID-19, China Journal of Infection and Public Health Coronavirus disease 2019 Epidemiology Incubation period High-risk susceptible people China |
| title | Public health initiatives from hospitalized patients with COVID-19, China |
| title_full | Public health initiatives from hospitalized patients with COVID-19, China |
| title_fullStr | Public health initiatives from hospitalized patients with COVID-19, China |
| title_full_unstemmed | Public health initiatives from hospitalized patients with COVID-19, China |
| title_short | Public health initiatives from hospitalized patients with COVID-19, China |
| title_sort | public health initiatives from hospitalized patients with covid 19 china |
| topic | Coronavirus disease 2019 Epidemiology Incubation period High-risk susceptible people China |
| url | http://www.sciencedirect.com/science/article/pii/S1876034120305232 |
| work_keys_str_mv | AT chenkaizhao publichealthinitiativesfromhospitalizedpatientswithcovid19china AT yueqinxu publichealthinitiativesfromhospitalizedpatientswithcovid19china AT xuzhang publichealthinitiativesfromhospitalizedpatientswithcovid19china AT yapingzhong publichealthinitiativesfromhospitalizedpatientswithcovid19china AT lilong publichealthinitiativesfromhospitalizedpatientswithcovid19china AT wenzhizhan publichealthinitiativesfromhospitalizedpatientswithcovid19china AT tingtingxu publichealthinitiativesfromhospitalizedpatientswithcovid19china AT chenzhan publichealthinitiativesfromhospitalizedpatientswithcovid19china AT yuehanchen publichealthinitiativesfromhospitalizedpatientswithcovid19china AT jinghaizhu publichealthinitiativesfromhospitalizedpatientswithcovid19china AT weixiao publichealthinitiativesfromhospitalizedpatientswithcovid19china AT miaohe publichealthinitiativesfromhospitalizedpatientswithcovid19china |