Ampelopsin attenuates 6-OHDA-induced neurotoxicity by regulating GSK-3β/NRF2/ARE signalling

Ampelopsin attenuates 6-OHDA-induced neurotoxicity by regulating GSK-3β/NRF2/ARE signalling

Increasing evidence has demonstrated that oxidative stress is involved in the pathogenesis of Parkinson's disease (PD), suggesting that pharmacological targeting of the antioxidant machinery may have therapeutic potential. Ampelopsin, a natural flavonoid compound, has been reported to possess v...

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Bibliographic Details
Main Authors: Xianjuan Kou, Jie Li, Jing Bian, Yi Yang, Xiaoqi Yang, Jingjing Fan, Shaohui Jia, Ning Chen
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Journal of Functional Foods
Subjects:
Ampelopsin
6-OHDA
Nrf2
GSK-3β
Oxidative stress
Parkinson's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615005071

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