Brucella abortus BspJ Is a Nucleomodulin That Inhibits Macrophage Apoptosis and Promotes Intracellular Survival of Brucella
To date, a variety of Brucella effector proteins have been found to mediate host cell secretion, autophagy, inflammation, and other signal pathways, but nuclear effector proteins have not yet been reported. We identified the first Brucella nucleomodulin, BspJ, and we screened out the BspJ interactio...
Main Authors: | Zhongchen Ma, Ruirui Li, Ruirui Hu, Xiaoyu Deng, Yimei Xu, Wei Zheng, Jihai Yi, Yong Wang, Chuangfu Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-11-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2020.599205/full |
Similar Items
-
Exosomes released by Brucella‐infected macrophages inhibit the intracellular survival of Brucella by promoting the polarization of M1 macrophages
by: Yueli Wang, et al.
Published: (2023-07-01) -
Interferon-Inducible Transmembrane Protein 3-Containing Exosome as a New Carrier for the Cell-to-Cell Transmission of Anti-Brucella Activity
by: Jihai Yi, et al.
Published: (2021-03-01) -
The deletion of omp19 gene of brucella abortus 2308 reduces its survival in mouse macrophage and in mice
by: Yueli WANG, et al.
Published: (2020-07-01) -
Anaplasma phagocytophilum Ats-1 enhances exosome secretion through Syntenin-1
by: Ruirui Li, et al.
Published: (2023-09-01) -
Multiomics analyses reveals Anaplasma phagocytophilum Ats-1 induces anti-apoptosis and energy metabolism by upregulating the respiratory chain-mPTP axis in eukaryotic mitochondria
by: Ruirui Li, et al.
Published: (2022-11-01)