Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology

Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology

Background: Retroelements (REs) are mobile genetic elements comprising ~40% of human DNA. They can reshape expression patterns of nearby genes by providing various regulatory sequences. The proportion of regulatory sequences held by REs can serve a measure of regulatory evolution rate of the respect...

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Bibliographic Details
Main Authors: Daniil Nikitin, Nikita Kolosov, Anastasiia Murzina, Karina Pats, Anton Zamyatin, Victor Tkachev, Maxim Sorokin, Philippe Kopylov, Anton Buzdin
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
human genome evolution
histone modifications
h3k4me1
enhancers of transcription
retrotransposons
retroelements
molecular pathways
gene ontology
epigenetics
gene expression regulation
Online Access:https://www.mdpi.com/2073-4409/8/10/1219

Internet

https://www.mdpi.com/2073-4409/8/10/1219

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