Major depletion of plasmacytoid dendritic cells in HIV-2 infection, an attenuated form of HIV disease.

Major depletion of plasmacytoid dendritic cells in HIV-2 infection, an attenuated form of HIV disease.

Plasmacytoid dendritic cells (pDC) provide an important link between innate and acquired immunity, mediating their action mainly through IFN-alpha production. pDC suppress HIV-1 replication, but there is increasing evidence suggesting they may also contribute to the increased levels of cell apoptosi...

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Bibliographic Details
Main Authors: Rita Cavaleiro, António P Baptista, Rui S Soares, Rita Tendeiro, Russell B Foxall, Perpétua Gomes, Rui M M Victorino, Ana E Sousa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2773933?pdf=render

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