Direct pathway cloning of the sodorifen biosynthetic gene cluster and recombinant generation of its product in E. coli

Direct pathway cloning of the sodorifen biosynthetic gene cluster and recombinant generation of its product in E. coli

Abstract Background Serratia plymuthica WS3236 was selected for whole genome sequencing based on preliminary genetic and chemical screening indicating the presence of multiple natural product pathways. This led to the identification of a putative sodorifen biosynthetic gene cluster (BGC). The natura...

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Bibliographic Details
Main Authors: Elke R. Duell, Paul M. D’Agostino, Nicole Shapiro, Tanja Woyke, Thilo M. Fuchs, Tobias A. M. Gulder
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Microbial Cell Factories
Subjects:
Sodorifen
Serratia plymuthica
Terpenes
Genome mining
DiPaC
Heterologous expression
Online Access:http://link.springer.com/article/10.1186/s12934-019-1080-6

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http://link.springer.com/article/10.1186/s12934-019-1080-6

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