Reduced expression of FRG1 facilitates breast cancer progression via GM-CSF/MEK-ERK axis by abating FRG1 mediated transcriptional repression of GM-CSF

Reduced expression of FRG1 facilitates breast cancer progression via GM-CSF/MEK-ERK axis by abating FRG1 mediated transcriptional repression of GM-CSF

Abstract Multiple molecular subtypes and distinct clinical outcomes in breast cancer, necessitate specific therapy. Moreover, despite the improvements in breast cancer therapy, it remains the fifth cause of cancer-related deaths, indicating the involvement of unknown genes. To identify novel contrib...

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Autors principals: Bratati Mukherjee, Ankit Tiwari, Ananya Palo, Niharika Pattnaik, Subrat Samantara, Manjusha Dixit
Format: Article
Idioma:English
Publicat: Nature Publishing Group 2022-11-01
Col·lecció:Cell Death Discovery
Accés en línia:https://doi.org/10.1038/s41420-022-01240-w

Internet

https://doi.org/10.1038/s41420-022-01240-w

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