New technology for large preparation of a series of bioactive polyphenols from by-products of vinification
Grape pomaces or vinification by-products are abundant and rich in polyphenols, particularly proanthocyanidins. During the last three decades, grape and wine polyphenols, particularly catechins (CATs) and oligomeric proanthocyanidins (OPCs) have attracted considerable attention of the international...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2023-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/full_html/2023/01/bioconf_oiv2022_02024/bioconf_oiv2022_02024.html |
| _version_ | 1811157544485257216 |
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| author | Sun Baoshan Zhang Shuting Li Lingxi Zhao Jian |
| author_facet | Sun Baoshan Zhang Shuting Li Lingxi Zhao Jian |
| author_sort | Sun Baoshan |
| collection | DOAJ |
| description | Grape pomaces or vinification by-products are abundant and rich in polyphenols, particularly proanthocyanidins. During the last three decades, grape and wine polyphenols, particularly catechins (CATs) and oligomeric proanthocyanidins (OPCs) have attracted considerable attention of the international scientific community, due essentially to their potential health-beneficial effects, related to their protective action towards cardiovascular disease and the oxygen free radical scavenger capacity. Such phenolic compounds have been proved to be the key components responsible for the health-beneficial effects of red wine. Furthermore, although the most widely recognized antioxidants are Vitamins A, C, and E, scientific research has shown that OPCs are likely the most powerful antioxidants known. Although various OPCs have been available in the market, they are generally very expensive due to the high cost of their production. As a consequence, the development of efficient methods for large-scale preparation of these bioactive compounds have still a challenging task for scientists. In this communication, we will present a new and efficient technology for large preparation of bioactive polyphenols from vinification by-products (grape seed and grape skin). On one hand, polymeric proanthocyanidins were transformed into a series of low- molecule-weight bioactive compounds using various degradation methods. On the other hand, High-Speed Countcurrent Chromatography (HSCCC), as a relative new separation technology for natural product preparation, was applied to large and efficient isolation of these bioactive compounds. |
| first_indexed | 2024-04-10T05:08:59Z |
| format | Article |
| id | doaj.art-0ddd13d8da994f76b78e32e4558767c3 |
| institution | Directory Open Access Journal |
| issn | 2117-4458 |
| language | English |
| last_indexed | 2024-04-10T05:08:59Z |
| publishDate | 2023-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj.art-0ddd13d8da994f76b78e32e4558767c32023-03-09T11:16:40ZengEDP SciencesBIO Web of Conferences2117-44582023-01-01560202410.1051/bioconf/20235602024bioconf_oiv2022_02024New technology for large preparation of a series of bioactive polyphenols from by-products of vinificationSun Baoshan0Zhang Shuting1Li Lingxi2Zhao Jian3Pólo de Inovação de Dois Portos, Instituto Nacional de Investigação Agrária e Veterinária, I.P., Quinta da AlmoinhaSchool of Functional Food and Wine, Shenyang Pharmaceutical UniversitySchool of Functional Food and Wine, Shenyang Pharmaceutical UniversitySchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical UniversityGrape pomaces or vinification by-products are abundant and rich in polyphenols, particularly proanthocyanidins. During the last three decades, grape and wine polyphenols, particularly catechins (CATs) and oligomeric proanthocyanidins (OPCs) have attracted considerable attention of the international scientific community, due essentially to their potential health-beneficial effects, related to their protective action towards cardiovascular disease and the oxygen free radical scavenger capacity. Such phenolic compounds have been proved to be the key components responsible for the health-beneficial effects of red wine. Furthermore, although the most widely recognized antioxidants are Vitamins A, C, and E, scientific research has shown that OPCs are likely the most powerful antioxidants known. Although various OPCs have been available in the market, they are generally very expensive due to the high cost of their production. As a consequence, the development of efficient methods for large-scale preparation of these bioactive compounds have still a challenging task for scientists. In this communication, we will present a new and efficient technology for large preparation of bioactive polyphenols from vinification by-products (grape seed and grape skin). On one hand, polymeric proanthocyanidins were transformed into a series of low- molecule-weight bioactive compounds using various degradation methods. On the other hand, High-Speed Countcurrent Chromatography (HSCCC), as a relative new separation technology for natural product preparation, was applied to large and efficient isolation of these bioactive compounds.https://www.bio-conferences.org/articles/bioconf/full_html/2023/01/bioconf_oiv2022_02024/bioconf_oiv2022_02024.html |
| spellingShingle | Sun Baoshan Zhang Shuting Li Lingxi Zhao Jian New technology for large preparation of a series of bioactive polyphenols from by-products of vinification BIO Web of Conferences |
| title | New technology for large preparation of a series of bioactive polyphenols from by-products of vinification |
| title_full | New technology for large preparation of a series of bioactive polyphenols from by-products of vinification |
| title_fullStr | New technology for large preparation of a series of bioactive polyphenols from by-products of vinification |
| title_full_unstemmed | New technology for large preparation of a series of bioactive polyphenols from by-products of vinification |
| title_short | New technology for large preparation of a series of bioactive polyphenols from by-products of vinification |
| title_sort | new technology for large preparation of a series of bioactive polyphenols from by products of vinification |
| url | https://www.bio-conferences.org/articles/bioconf/full_html/2023/01/bioconf_oiv2022_02024/bioconf_oiv2022_02024.html |
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