Concomitant Rotavirus and Salmonella Infections in Children with Acute Diarrhea
The incidence of concomitant rotavirus and Salmonella infection has been reported to be 1.3% to 7.4%. We designed this study to compare the clinical manifestations in children infected with rotavirus, Salmonella, or both. Methods: The medical records of admitted children with acute rotavirus or Salm...
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| Format: | Article |
| Language: | English |
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Elsevier
2009-02-01
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| Series: | Pediatrics and Neonatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957209600231 |
| _version_ | 1819090277440159744 |
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| author | Wen-Tzong Lan Hung-Chang Lee Chun-Yan Yeung Chuen-Bin Jiang Hsin-An Kao Han-Yang Hung Nan-Chang Chiu |
| author_facet | Wen-Tzong Lan Hung-Chang Lee Chun-Yan Yeung Chuen-Bin Jiang Hsin-An Kao Han-Yang Hung Nan-Chang Chiu |
| author_sort | Wen-Tzong Lan |
| collection | DOAJ |
| description | The incidence of concomitant rotavirus and Salmonella infection has been reported to be 1.3% to 7.4%. We designed this study to compare the clinical manifestations in children infected with rotavirus, Salmonella, or both.
Methods: The medical records of admitted children with acute rotavirus or Salmonella gastroenteritis in 2001 were reviewed. They were divided into group R (rotavirus), group S (Salmonella) and group C (concomitant infection with both). The differences of clinical manifestations and laboratory data among the three groups were analyzed via chi-squared, analysis of variance (ANOVA), Bonferroni and Kruskal-Wallis tests, and odds ratios with 95% confidence intervals (95% CI).
Results: Among the 895 cases reviewed, 550 were group R, 312 group S, and 33 (3.7%) group C. Group C had more vomiting compared with group S (p = 0.0017). Comparing with group R, group C had more prolonged and high fever (≥ 39°C) (p< 0.05), more percentage of green coloration, with mucus and blood contained in the stool (p < 0.001). The C-reactive protein (CRP) value was significantly higher in group C (9.70 ± 11.05 mg/dL) than in group R (1.33 ± 3.62 mg/dL) or S (5.22 ± 6.11 mg/dL) (p < 0.05). Hypokalemia was found most frequently in group C (C: 30.0%, S: 8.8%, R: 7.3%) (p = 0.0026).
Conclusion: Concomitant rotavirus and Salmonella infections accounted for 3.7% of cases in this study. Patients in group C (30.0%) had a significantly higher incidence of hypokalemia than group R (7.3%) or S (8.8%). Group C consisted of 33 cases of the 895 reviewed cases (3.7%). In a child with rotavirus gastroenteritis, concomitant infection with Salmonella should be considered if the child has sustained a high fever (≥ 39°C) for over 4 days and a green stool with mucus and blood. |
| first_indexed | 2024-12-21T22:21:16Z |
| format | Article |
| id | doaj.art-0ddf3696a7f546e0ae77ac229d412636 |
| institution | Directory Open Access Journal |
| issn | 1875-9572 |
| language | English |
| last_indexed | 2024-12-21T22:21:16Z |
| publishDate | 2009-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj.art-0ddf3696a7f546e0ae77ac229d4126362022-12-21T18:48:19ZengElsevierPediatrics and Neonatology1875-95722009-02-0150181210.1016/S1875-9572(09)60023-1Concomitant Rotavirus and Salmonella Infections in Children with Acute DiarrheaWen-Tzong Lan0Hung-Chang Lee1Chun-Yan Yeung2Chuen-Bin Jiang3Hsin-An Kao4Han-Yang Hung5Nan-Chang Chiu6Department of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanThe incidence of concomitant rotavirus and Salmonella infection has been reported to be 1.3% to 7.4%. We designed this study to compare the clinical manifestations in children infected with rotavirus, Salmonella, or both. Methods: The medical records of admitted children with acute rotavirus or Salmonella gastroenteritis in 2001 were reviewed. They were divided into group R (rotavirus), group S (Salmonella) and group C (concomitant infection with both). The differences of clinical manifestations and laboratory data among the three groups were analyzed via chi-squared, analysis of variance (ANOVA), Bonferroni and Kruskal-Wallis tests, and odds ratios with 95% confidence intervals (95% CI). Results: Among the 895 cases reviewed, 550 were group R, 312 group S, and 33 (3.7%) group C. Group C had more vomiting compared with group S (p = 0.0017). Comparing with group R, group C had more prolonged and high fever (≥ 39°C) (p< 0.05), more percentage of green coloration, with mucus and blood contained in the stool (p < 0.001). The C-reactive protein (CRP) value was significantly higher in group C (9.70 ± 11.05 mg/dL) than in group R (1.33 ± 3.62 mg/dL) or S (5.22 ± 6.11 mg/dL) (p < 0.05). Hypokalemia was found most frequently in group C (C: 30.0%, S: 8.8%, R: 7.3%) (p = 0.0026). Conclusion: Concomitant rotavirus and Salmonella infections accounted for 3.7% of cases in this study. Patients in group C (30.0%) had a significantly higher incidence of hypokalemia than group R (7.3%) or S (8.8%). Group C consisted of 33 cases of the 895 reviewed cases (3.7%). In a child with rotavirus gastroenteritis, concomitant infection with Salmonella should be considered if the child has sustained a high fever (≥ 39°C) for over 4 days and a green stool with mucus and blood.http://www.sciencedirect.com/science/article/pii/S1875957209600231acute gastroenteritisconcomitant infectionrotavirusSalmonella |
| spellingShingle | Wen-Tzong Lan Hung-Chang Lee Chun-Yan Yeung Chuen-Bin Jiang Hsin-An Kao Han-Yang Hung Nan-Chang Chiu Concomitant Rotavirus and Salmonella Infections in Children with Acute Diarrhea Pediatrics and Neonatology acute gastroenteritis concomitant infection rotavirus Salmonella |
| title | Concomitant Rotavirus and Salmonella Infections in Children with Acute Diarrhea |
| title_full | Concomitant Rotavirus and Salmonella Infections in Children with Acute Diarrhea |
| title_fullStr | Concomitant Rotavirus and Salmonella Infections in Children with Acute Diarrhea |
| title_full_unstemmed | Concomitant Rotavirus and Salmonella Infections in Children with Acute Diarrhea |
| title_short | Concomitant Rotavirus and Salmonella Infections in Children with Acute Diarrhea |
| title_sort | concomitant rotavirus and salmonella infections in children with acute diarrhea |
| topic | acute gastroenteritis concomitant infection rotavirus Salmonella |
| url | http://www.sciencedirect.com/science/article/pii/S1875957209600231 |
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