Determination of 9 halogenated alkanes in toothpaste by GC⁃MS
ObjectiveTo establish a GC-MS method for the detection of 9 halogenated alkanes in toothpastes.MethodsVarious brands of toothpastes on the market were collected as the samples. Methanol was used as the extraction solution. After shaking， vortex and centrifugation， the supernatant was filtered by 0.4...
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| Format: | Article |
| Language: | zho |
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Shanghai Preventive Medicine Association
2023-09-01
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| Series: | Shanghai yufang yixue |
| Subjects: | |
| Online Access: | http://www.sjpm.org.cn/cn/article/doi/10.19428/j.cnki.sjpm.2023.22959 |
| _version_ | 1797405548787793920 |
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| author | PENG Qian LIN Xi WU Linying XUAN Dongliang |
| author_facet | PENG Qian LIN Xi WU Linying XUAN Dongliang |
| author_sort | PENG Qian |
| collection | DOAJ |
| description | ObjectiveTo establish a GC-MS method for the detection of 9 halogenated alkanes in toothpastes.MethodsVarious brands of toothpastes on the market were collected as the samples. Methanol was used as the extraction solution. After shaking， vortex and centrifugation， the supernatant was filtered by 0.45 μm microporous filter membrane. The content of 9 halogenated alkanes including chloromethane， dichloromethane， chloroform， 1，1，1-trichloroethane， carbon tetrachloride， 1，2-dichloroethane， 1，1，2-trichloroethane， 1，2-dibromoethane， 1，2，3-trichloropropane in the filtrate were determined by GC-MS.ResultsThe 9 halogenated alkanes showed a good linear relationship in the concentration range of 0.03‒1.00 μg·mL-1. The correlation coefficient was ≥0.998 7 with the detection limits of 0.015‒0.056 mg·kg-1. The spiked recoveries were 83.2%‒108.9% with the RSD of 2.0%‒9.8%. In the actual sample analysis， 1，1，2-trichloroethane and 1，2，3-trichloropropane were respectively detected in 6 toothpaste samples from 5 brands.ConclusionThe method is simple， sensitive， accurate， and has good spiked recoveries. It can be used for the determination of halogenated alkanes in toothpastes. |
| first_indexed | 2024-03-09T03:11:35Z |
| format | Article |
| id | doaj.art-0de00d7247ff429498d4a14b9e44dd92 |
| institution | Directory Open Access Journal |
| issn | 1004-9231 |
| language | zho |
| last_indexed | 2024-03-09T03:11:35Z |
| publishDate | 2023-09-01 |
| publisher | Shanghai Preventive Medicine Association |
| record_format | Article |
| series | Shanghai yufang yixue |
| spelling | doaj.art-0de00d7247ff429498d4a14b9e44dd922023-12-04T02:14:35ZzhoShanghai Preventive Medicine AssociationShanghai yufang yixue1004-92312023-09-0135990590910.19428/j.cnki.sjpm.2023.229591004-9231（2023）09-0905-05Determination of 9 halogenated alkanes in toothpaste by GC⁃MSPENG QianLIN XiWU LinyingXUAN DongliangObjectiveTo establish a GC-MS method for the detection of 9 halogenated alkanes in toothpastes.MethodsVarious brands of toothpastes on the market were collected as the samples. Methanol was used as the extraction solution. After shaking， vortex and centrifugation， the supernatant was filtered by 0.45 μm microporous filter membrane. The content of 9 halogenated alkanes including chloromethane， dichloromethane， chloroform， 1，1，1-trichloroethane， carbon tetrachloride， 1，2-dichloroethane， 1，1，2-trichloroethane， 1，2-dibromoethane， 1，2，3-trichloropropane in the filtrate were determined by GC-MS.ResultsThe 9 halogenated alkanes showed a good linear relationship in the concentration range of 0.03‒1.00 μg·mL-1. The correlation coefficient was ≥0.998 7 with the detection limits of 0.015‒0.056 mg·kg-1. The spiked recoveries were 83.2%‒108.9% with the RSD of 2.0%‒9.8%. In the actual sample analysis， 1，1，2-trichloroethane and 1，2，3-trichloropropane were respectively detected in 6 toothpaste samples from 5 brands.ConclusionThe method is simple， sensitive， accurate， and has good spiked recoveries. It can be used for the determination of halogenated alkanes in toothpastes.http://www.sjpm.org.cn/cn/article/doi/10.19428/j.cnki.sjpm.2023.22959halogenated alkanetoothpastegc-msdetermination |
| spellingShingle | PENG Qian LIN Xi WU Linying XUAN Dongliang Determination of 9 halogenated alkanes in toothpaste by GC⁃MS Shanghai yufang yixue halogenated alkane toothpaste gc-ms determination |
| title | Determination of 9 halogenated alkanes in toothpaste by GC⁃MS |
| title_full | Determination of 9 halogenated alkanes in toothpaste by GC⁃MS |
| title_fullStr | Determination of 9 halogenated alkanes in toothpaste by GC⁃MS |
| title_full_unstemmed | Determination of 9 halogenated alkanes in toothpaste by GC⁃MS |
| title_short | Determination of 9 halogenated alkanes in toothpaste by GC⁃MS |
| title_sort | determination of 9 halogenated alkanes in toothpaste by gc⁃ms |
| topic | halogenated alkane toothpaste gc-ms determination |
| url | http://www.sjpm.org.cn/cn/article/doi/10.19428/j.cnki.sjpm.2023.22959 |
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