Oxidized low density lipoprotein induced caspase-1 mediated pyroptotic cell death in macrophages: implication in lesion instability?
Macrophage death in advanced lesion has been confirmed to play an important role in plaque instability. However, the mechanism underlying lesion macrophage death still remains largely unknown.Immunohistochemistry showed that caspase-1 activated in advanced lesion and co-located with macrophages and...
Main Authors: | Jing Lin, Xiling Shou, Xiaobo Mao, Jiangchuan Dong, Nilesh Mohabeer, Kishan Kumar Kushwaha, Lei Wang, Yousu Su, Hongcheng Fang, Dazhu Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3636212?pdf=render |
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