Antithrombotic drugs with adjuvant action against COVID-19
Waiting for the vaccine and/or the best antiviral treatment for coronavirus infection disease 2019 (COVID-19), after its outbreak in China at the beginning of 2020 and its viral diffusion around the world in the following weeks, several drugs have been suggested for their potential adjuvant support...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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PAGEPress Publications
2020-12-01
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Series: | Italian Journal of Medicine |
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Online Access: | https://www.italjmed.org/index.php/ijm/article/view/1348 |
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author | Pierpaolo Di Micco Gianluca Di Micco Vincenzo Russo Andrea Fontanella |
author_facet | Pierpaolo Di Micco Gianluca Di Micco Vincenzo Russo Andrea Fontanella |
author_sort | Pierpaolo Di Micco |
collection | DOAJ |
description | Waiting for the vaccine and/or the best antiviral treatment for coronavirus infection disease 2019 (COVID-19), after its outbreak in China at the beginning of 2020 and its viral diffusion around the world in the following weeks, several drugs have been suggested for their potential adjuvant support against infection. Several drugs have been suggested to have a potential ancillary antiviral role. Circulating proteins, in particular proteases and peptidases regulated by drug functions, may interact with well-known drugs like anticoagulants, antihypertensives, antiserotoninergics, and so also with viral proteases. We here report a brief list of these drugs (i.e., heparinoids, flavonoids, antiplatelets, anticoagulants) that may interact with COVID-19. |
first_indexed | 2024-03-09T09:07:40Z |
format | Article |
id | doaj.art-0de4721341694dd9ac9dfae9b55a5a2a |
institution | Directory Open Access Journal |
issn | 1877-9344 1877-9352 |
language | English |
last_indexed | 2024-03-09T09:07:40Z |
publishDate | 2020-12-01 |
publisher | PAGEPress Publications |
record_format | Article |
series | Italian Journal of Medicine |
spelling | doaj.art-0de4721341694dd9ac9dfae9b55a5a2a2023-12-02T09:33:56ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522020-12-0114410.4081/itjm.2020.1348Antithrombotic drugs with adjuvant action against COVID-19Pierpaolo Di Micco0Gianluca Di Micco1Vincenzo Russo2Andrea Fontanella3Internal Medicine Department, Emergency Room Unit, Fatebenefratelli Hospital, NaplesDiagnostic Center Varelli, NaplesDepartment of Translational Medical Sciences, University of Campania Luigi Vanvitelli - Monaldi Hospital, NaplesInternal Medicine Department, Emergency Room Unit, Fatebenefratelli Hospital, NaplesWaiting for the vaccine and/or the best antiviral treatment for coronavirus infection disease 2019 (COVID-19), after its outbreak in China at the beginning of 2020 and its viral diffusion around the world in the following weeks, several drugs have been suggested for their potential adjuvant support against infection. Several drugs have been suggested to have a potential ancillary antiviral role. Circulating proteins, in particular proteases and peptidases regulated by drug functions, may interact with well-known drugs like anticoagulants, antihypertensives, antiserotoninergics, and so also with viral proteases. We here report a brief list of these drugs (i.e., heparinoids, flavonoids, antiplatelets, anticoagulants) that may interact with COVID-19.https://www.italjmed.org/index.php/ijm/article/view/1348COVID-19flavonoidsheparinanticoagulantsfondaparinux. |
spellingShingle | Pierpaolo Di Micco Gianluca Di Micco Vincenzo Russo Andrea Fontanella Antithrombotic drugs with adjuvant action against COVID-19 Italian Journal of Medicine COVID-19 flavonoids heparin anticoagulants fondaparinux. |
title | Antithrombotic drugs with adjuvant action against COVID-19 |
title_full | Antithrombotic drugs with adjuvant action against COVID-19 |
title_fullStr | Antithrombotic drugs with adjuvant action against COVID-19 |
title_full_unstemmed | Antithrombotic drugs with adjuvant action against COVID-19 |
title_short | Antithrombotic drugs with adjuvant action against COVID-19 |
title_sort | antithrombotic drugs with adjuvant action against covid 19 |
topic | COVID-19 flavonoids heparin anticoagulants fondaparinux. |
url | https://www.italjmed.org/index.php/ijm/article/view/1348 |
work_keys_str_mv | AT pierpaolodimicco antithromboticdrugswithadjuvantactionagainstcovid19 AT gianlucadimicco antithromboticdrugswithadjuvantactionagainstcovid19 AT vincenzorusso antithromboticdrugswithadjuvantactionagainstcovid19 AT andreafontanella antithromboticdrugswithadjuvantactionagainstcovid19 |