Development of a humanized HLA‐A30 transgenic mouse model

Development of a humanized HLA‐A30 transgenic mouse model

Abstract Background There are remarkable genetic differences between animal major histocompatibility complex (MHC) systems and the human leukocyte antigen (HLA) system. HLA transgenic humanized mouse model systems offer a much better method to study the HLA‐A‐related principal mechanisms for vaccine...

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Bibliographic Details
Main Authors: Meng‐min Zhu, Bo‐wen Niu, Ling‐ling Liu, Hua Yang, Bo‐yin Qin, Xiu‐hua Peng, Li‐xiang Chen, Yang Liu, Chao Wang, Xiao‐nan Ren, Chun‐hua Xu, Xiao‐hui Zhou, Feng Li
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Animal Models and Experimental Medicine
Subjects:
HLA‐A30
humanized mouse
immunology
major histocompatibility complex (MHC)
Online Access:https://doi.org/10.1002/ame2.12225

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