SURVEILLANCE OF PATIENTS WITH DIFFUSE GASTRIC CANCER ASSOCIATED WITH HEREDITARY MUTATIONS
Worldwide the gastric cancer holds fifth place above all oncological diseases and the third among the most common causes of death from cancer, the total number of deaths per year is estimated at 723 000. The vast majority of cases of the gastric cancer are sporadic, but it is known that 1–3% are a m...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Science and Innovation Center Publishing House
2018-03-01
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| Series: | В мире научных открытий |
| Subjects: | |
| Online Access: | http://journal-s.org/index.php/vmno/article/view/10572 |
| Summary: | Worldwide the gastric cancer holds fifth place above all oncological diseases and the third among the most common causes of death from cancer, the total number of deaths per year is estimated at 723 000. The vast majority of cases of the gastric cancer are sporadic, but it is known that 1–3% are a manifestation of the hereditary forms and syndromes. This article is dedicated to the new trends and strategies in the management of the risk of the hereditary diffuse gastric cancer. The basics of genetic counseling and current criteria for selecting families are covered, in the aim of analyzing hereditary mutations. The problems of endoscopic screening and dynamic monitoring of the gastric mucosa are discussed. A possible approach of the surgical treatment as preventive gastrectomy is discussed. The features of morphological studies in hereditary diffuse gastric cancer are outlined. The principles of postoperative care are covered. The prospects of medical support for patients with hereditary diffuse stomach cancer are reviewed. |
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| ISSN: | 2072-0831 2307-9428 |