IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis

IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis

Summary: Cardiac dysfunction is a well-recognized complication of sepsis and seriously affects the prognosis of sepsis patients. IL-30 has been reported to exert anti-inflammatory effects in various diseases. However, the role of IL-30 in sepsis-induced myocardial dysfunction (SIMD) remains unclear....

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Bibliographic Details
Main Authors: Mengmeng Zhao, Zihui Zheng, Pingan Zhang, Yao Xu, Jishou Zhang, Shanshan Peng, Jianfang Liu, Wei Pan, Zheng Yin, Shuwan Xu, Cheng Wei, Jun Wan, Menglong Wang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Molecular biology
Immunology
Immune response
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223016218

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