A dual Ucp1 reporter mouse model for imaging and quantitation of brown and brite fat recruitment
Objectives: Brown adipose tissue (BAT) dissipates nutritional energy as heat through uncoupling protein 1 (UCP1). The discovery of functional BAT in healthy adult humans has promoted the search for pharmacological interventions to recruit and activate brown fat as a treatment of obesity and diabetes...
Main Authors: | Hui Wang, Monja Willershäuser, Angelos Karlas, Dimitris Gorpas, Josefine Reber, Vasilis Ntziachristos, Stefanie Maurer, Tobias Fromme, Yongguo Li, Martin Klingenspor |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-02-01
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Series: | Molecular Metabolism |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877818308846 |
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