Fullerene and apoptosis
Fullerene derivatives superfamily attracts a serious attention as antiviral and anticancer agents and drug delivery carriers as well. A large number of such fullerene С60 derivatives obtained to date. However, there is an obvious deficit of information about causes and mechanisms of immediately and...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2014-07-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/46 |
| _version_ | 1797855584781860864 |
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| author | M. A. Orlova T. P. Trofimova A. P. Orlov O. A. Shatalov Yu. K. Napolov A. A. Svistunov V. P. Chekhonin |
| author_facet | M. A. Orlova T. P. Trofimova A. P. Orlov O. A. Shatalov Yu. K. Napolov A. A. Svistunov V. P. Chekhonin |
| author_sort | M. A. Orlova |
| collection | DOAJ |
| description | Fullerene derivatives superfamily attracts a serious attention as antiviral and anticancer agents and drug delivery carriers as well. A large number of such fullerene С60 derivatives obtained to date. However, there is an obvious deficit of information about causes and mechanisms of immediately and long-term consequences of their effects in vivo which is a true obstacle on the way leading to practical medical use of them. First, this concerns their impact on the proliferation, apoptosis and necrosis regulation. Fullerene nanoparticle functionalization type, their sizes and surface nanopathology are of great importance to further promoting of either cytoprotective or cytotoxic effects. This lecture provides modern concept analysis regarding fullerenes effects on apoptosis pathway in normal and tumor cells. |
| first_indexed | 2024-04-09T20:24:58Z |
| format | Article |
| id | doaj.art-0df0582a0afc4412987075c4a32f3cb1 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2024-04-09T20:24:58Z |
| publishDate | 2014-07-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-0df0582a0afc4412987075c4a32f3cb12023-03-30T20:15:09ZrusABV-pressОнкогематология1818-83462413-40232014-07-0181657110.17650/1818-8346-2013-8-1-65-7161Fullerene and apoptosisM. A. Orlova0T. P. Trofimova1A. P. Orlov2O. A. Shatalov3Yu. K. Napolov4A. A. Svistunov5V. P. Chekhonin6M.V. Lomonosov Moscow State UniversityM.V. Lomonosov Moscow State UniversityN.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaI.M. Sechenov Moscow State Medical University, Ministry of Health of RussiaI.M. Sechenov Moscow State Medical University, Ministry of Health of RussiaI.M. Sechenov Moscow State Medical University, Ministry of Health of RussiaN.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaFullerene derivatives superfamily attracts a serious attention as antiviral and anticancer agents and drug delivery carriers as well. A large number of such fullerene С60 derivatives obtained to date. However, there is an obvious deficit of information about causes and mechanisms of immediately and long-term consequences of their effects in vivo which is a true obstacle on the way leading to practical medical use of them. First, this concerns their impact on the proliferation, apoptosis and necrosis regulation. Fullerene nanoparticle functionalization type, their sizes and surface nanopathology are of great importance to further promoting of either cytoprotective or cytotoxic effects. This lecture provides modern concept analysis regarding fullerenes effects on apoptosis pathway in normal and tumor cells.https://oncohematology.abvpress.ru/ongm/article/view/46fullerenesapoptosissignaling pathway |
| spellingShingle | M. A. Orlova T. P. Trofimova A. P. Orlov O. A. Shatalov Yu. K. Napolov A. A. Svistunov V. P. Chekhonin Fullerene and apoptosis Онкогематология fullerenes apoptosis signaling pathway |
| title | Fullerene and apoptosis |
| title_full | Fullerene and apoptosis |
| title_fullStr | Fullerene and apoptosis |
| title_full_unstemmed | Fullerene and apoptosis |
| title_short | Fullerene and apoptosis |
| title_sort | fullerene and apoptosis |
| topic | fullerenes apoptosis signaling pathway |
| url | https://oncohematology.abvpress.ru/ongm/article/view/46 |
| work_keys_str_mv | AT maorlova fullereneandapoptosis AT tptrofimova fullereneandapoptosis AT aporlov fullereneandapoptosis AT oashatalov fullereneandapoptosis AT yuknapolov fullereneandapoptosis AT aasvistunov fullereneandapoptosis AT vpchekhonin fullereneandapoptosis |