Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PET

Penile metastases are a rare entity and are associated with widespread metastatic disease. It is associated with significant morbidity with a poor prognosis. There have been few case reports about metastatic prostate adenocarcinoma to the penis. Diagnosis is often clinical, however, the use of PSMA...

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Main Authors: Matthew Chau, Nicole Swarbrick, Sunny Lee
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442022003126
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author Matthew Chau
Nicole Swarbrick
Sunny Lee
author_facet Matthew Chau
Nicole Swarbrick
Sunny Lee
author_sort Matthew Chau
collection DOAJ
description Penile metastases are a rare entity and are associated with widespread metastatic disease. It is associated with significant morbidity with a poor prognosis. There have been few case reports about metastatic prostate adenocarcinoma to the penis. Diagnosis is often clinical, however, the use of PSMA PET has a high sensitivity. We report the first case of metastatic castration resistant prostate cancer with an isolated penile metastatic site. This was not identified on conventional staging or PSMA PET, but using FDG PET. A radical penectomy was performed with ongoing survival.
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spelling doaj.art-0df12f1d8b5e4b0994281bf6c3e1b8362023-01-26T04:45:09ZengElsevierUrology Case Reports2214-44202023-01-0146102300Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PETMatthew Chau0Nicole Swarbrick1Sunny Lee2Department of Urology, Royal Perth Hospital, Perth, WA, Australia; Corresponding author. Current address: Department of Urology, Level 11, Royal Perth Hospital, Victoria Square, Perth, WA, 6000, Australia.Department of Anatomical Pathology, Path West Laboratory Medicine, Perth, WA, Australia; Division of Pathology and Laboratory Medicine, Medical School, University of Western, AustraliaDepartment of Urology, Royal Perth Hospital, Perth, WA, AustraliaPenile metastases are a rare entity and are associated with widespread metastatic disease. It is associated with significant morbidity with a poor prognosis. There have been few case reports about metastatic prostate adenocarcinoma to the penis. Diagnosis is often clinical, however, the use of PSMA PET has a high sensitivity. We report the first case of metastatic castration resistant prostate cancer with an isolated penile metastatic site. This was not identified on conventional staging or PSMA PET, but using FDG PET. A radical penectomy was performed with ongoing survival.http://www.sciencedirect.com/science/article/pii/S2214442022003126Prostate cancerMetastaticPET scan
spellingShingle Matthew Chau
Nicole Swarbrick
Sunny Lee
Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PET
Urology Case Reports
Prostate cancer
Metastatic
PET scan
title Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PET
title_full Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PET
title_fullStr Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PET
title_full_unstemmed Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PET
title_short Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PET
title_sort isolated psma negative penile metastasis from castration resistant prostate adenocarcinoma identified by fdg pet
topic Prostate cancer
Metastatic
PET scan
url http://www.sciencedirect.com/science/article/pii/S2214442022003126
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AT sunnylee isolatedpsmanegativepenilemetastasisfromcastrationresistantprostateadenocarcinomaidentifiedbyfdgpet