Optical dispersions through intracellular inhomogeneities
The transport of intensity equation (TIE) exhibits a noninterferometric correlation between the intensity and phase variations of intermediate fields (e.g., light and electrons) in biological imaging. Previous TIE formulations have generally assumed free-space propagation of monochromatic, coherent...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Physical Society
2023-05-01
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| Series: | Physical Review Research |
| Online Access: | http://doi.org/10.1103/PhysRevResearch.5.L022043 |
| _version_ | 1797210419830456320 |
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| author | Masaki Watabe Yasuhiro Hirano Atsuko Iwane Osamu Matoba Koichi Takahashi |
| author_facet | Masaki Watabe Yasuhiro Hirano Atsuko Iwane Osamu Matoba Koichi Takahashi |
| author_sort | Masaki Watabe |
| collection | DOAJ |
| description | The transport of intensity equation (TIE) exhibits a noninterferometric correlation between the intensity and phase variations of intermediate fields (e.g., light and electrons) in biological imaging. Previous TIE formulations have generally assumed free-space propagation of monochromatic, coherent field functions crossing phase distributions along a longitudinal direction. In this study, we modify the TIE with fractal (or self-similar) organization models based on intracellular refractive index turbulence. We then implement TIE simulations over a broad range of fractal dimensions and wavelengths. Simulation results show how the intensity propagation through the spatial fluctuation of intracellular refractive index interconnects fractal dimensionality with intensity dispersion (or transmissivity) within the picometer to micrometer wavelength range. Additionally, we provide a spatial autocorrelation of phase derivatives, which allows for the direct measurement and reconstruction of intracellular fractal profiles from optical and electron microscopy imaging. |
| first_indexed | 2024-04-24T10:10:18Z |
| format | Article |
| id | doaj.art-0df37925397741d8985e15a1f30e8591 |
| institution | Directory Open Access Journal |
| issn | 2643-1564 |
| language | English |
| last_indexed | 2024-04-24T10:10:18Z |
| publishDate | 2023-05-01 |
| publisher | American Physical Society |
| record_format | Article |
| series | Physical Review Research |
| spelling | doaj.art-0df37925397741d8985e15a1f30e85912024-04-12T17:31:19ZengAmerican Physical SocietyPhysical Review Research2643-15642023-05-0152L02204310.1103/PhysRevResearch.5.L022043Optical dispersions through intracellular inhomogeneitiesMasaki WatabeYasuhiro HiranoAtsuko IwaneOsamu MatobaKoichi TakahashiThe transport of intensity equation (TIE) exhibits a noninterferometric correlation between the intensity and phase variations of intermediate fields (e.g., light and electrons) in biological imaging. Previous TIE formulations have generally assumed free-space propagation of monochromatic, coherent field functions crossing phase distributions along a longitudinal direction. In this study, we modify the TIE with fractal (or self-similar) organization models based on intracellular refractive index turbulence. We then implement TIE simulations over a broad range of fractal dimensions and wavelengths. Simulation results show how the intensity propagation through the spatial fluctuation of intracellular refractive index interconnects fractal dimensionality with intensity dispersion (or transmissivity) within the picometer to micrometer wavelength range. Additionally, we provide a spatial autocorrelation of phase derivatives, which allows for the direct measurement and reconstruction of intracellular fractal profiles from optical and electron microscopy imaging.http://doi.org/10.1103/PhysRevResearch.5.L022043 |
| spellingShingle | Masaki Watabe Yasuhiro Hirano Atsuko Iwane Osamu Matoba Koichi Takahashi Optical dispersions through intracellular inhomogeneities Physical Review Research |
| title | Optical dispersions through intracellular inhomogeneities |
| title_full | Optical dispersions through intracellular inhomogeneities |
| title_fullStr | Optical dispersions through intracellular inhomogeneities |
| title_full_unstemmed | Optical dispersions through intracellular inhomogeneities |
| title_short | Optical dispersions through intracellular inhomogeneities |
| title_sort | optical dispersions through intracellular inhomogeneities |
| url | http://doi.org/10.1103/PhysRevResearch.5.L022043 |
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