NR2F2 Regulates Cell Proliferation and Immunomodulation in Whartons’ Jelly Stem Cells

NR2F2 Regulates Cell Proliferation and Immunomodulation in Whartons’ Jelly Stem Cells

(1) Background: Wharton’s Jelly stem cells (WJ-MSCs) are multipotent mesenchymal stem cells that can proliferate rapidly and have low immunogenicity. Therefore, WJ-MSCs have gained considerable attention in the fields of immunomodulation and disease treatment and have entered clinical trials for the...

Full description

Bibliographic Details
Main Authors:	Li Ma, Min Huang, Xiaohua Liao, Xiyu Cai, Qiang Wu
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	Genes
Subjects:	WJ-MSCs NR2F2 RNA-seq gene regulatory network cell cycle immunomodulation
Online Access:	https://www.mdpi.com/2073-4425/13/8/1458

Similar Items

The Molecular Regulatory Mechanism in Multipotency and Differentiation of Wharton’s Jelly Stem Cells
by: Li Ma, et al.
Published: (2023-08-01)

Wharton’s Jelly Mesenchymal Stem Cells: Differentiation Capacity Showing its Role in Bone Tissue Engineering
by: Rizal Rizal, et al.
Published: (2020-11-01)

Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells
by: Mathiyazhagan Rengasamy, et al.
Published: (2017-06-01)

Possible Underlying Mechanisms for the Renoprotective Effect of Retinoic Acid-Pretreated Wharton’s Jelly Mesenchymal Stem Cells against Renal Ischemia/Reperfusion Injury
by: Mai Barakat, et al.
Published: (2022-06-01)

Wharton’s jelly mesenchymal stem cells: a concise review of their secretome and prospective clinical applications
by: Hana Drobiova, et al.
Published: (2023-06-01)

Nanosheets Based Approach to Elevate the Proliferative and Differentiation Efficacy of Human Wharton’s Jelly Mesenchymal Stem Cells
by: Suraj Kumar Singh, et al.
Published: (2022-05-01)

Human Wharton's jelly-derived mesenchymal stem cells alleviate concanavalin A-induced fulminant hepatitis by repressing NF-κB signaling and glycolysis
by: Lijie Pan, et al.
Published: (2021-09-01)

Ethionamide Preconditioning Enhances the Proliferation and Migration of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells
by: Na-Hee Lee, et al.
Published: (2020-09-01)

Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation
by: Beatriz Hernaez-Estrada, et al.
Published: (2022-01-01)

The Effect of Proinflammatory Cytokines on the Proliferation, Migration and Secretory Activity of Mesenchymal Stem/Stromal Cells (WJ-MSCs) under 5% O<sub>2</sub> and 21% O<sub>2</sub> Culture Conditions
by: Aleksandra Wedzinska, et al.
Published: (2021-04-01)

Cloning and phylogenetic analysis of NMDA receptor subunits NR1, NR2A and NR2B in Xenopus laevis tadpoles
by: Rebecca C Ewald, et al.
Published: (2009-09-01)

The Effect of Mesenchymal Stem Cells on the Expression of IDOand Qa2 Molecules in Dendritic Cells
by: Ali Moravej, et al.
Published: (2019-02-01)

BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory response
by: Ahui Song, et al.
Published: (2020-10-01)

Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro
by: Changbin Sun, et al.
Published: (2020-04-01)

Immunomodulation and Regenerative Capacity of MSCs for Long-COVID
by: Xin Ya Loke, et al.
Published: (2021-11-01)

NR5A1 and NR5A2 regulate follicle development in chicken (Gallus gallus) by altering proliferation, apoptosis, and steroid hormone synthesis of granulosa cells
by: Ruixue Nie, et al.
Published: (2024-05-01)

Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of KITLG and DKK1 genes in glioma SCs in vitro
by: Nazneen Aslam, et al.
Published: (2021-03-01)

Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair
by: Luz Correa-Araujo, et al.
Published: (2023-10-01)

Neuroprotective Mechanisms of Lycium barbarum Polysaccharides Against Ischemic Insults by Regulating NR2B and NR2A Containing NMDA Receptor Signaling Pathways
by: Zhongshan Shi, et al.
Published: (2017-09-01)

Metabolic Reconfiguration Activates Stemness and Immunomodulation of PDLSCs
by: Payal Arora, et al.
Published: (2022-04-01)

The RYR3 gene is involved in Wharton’s jelly derived mesenchymal stem cell treatment of Alzheimer’s disease in rats
by: Hirowati Ali, et al.
Published: (2023-05-01)

Antibacterial and Immunomodulatory Properties of Acellular Wharton’s Jelly Matrix
by: Marie Dubus, et al.
Published: (2022-01-01)

The expression mechanism of programmed cell death 1 ligand 1 and its role in immunomodulatory ability of mesenchymal stem cells
by: Zhuo Chen, et al.
Published: (2024-01-01)

Role of NR4A family members in myeloid cells and leukemia
by: Salix Boulet, et al.
Published: (2022-01-01)

LncRNA NR2F1-AS1 inhibits the malignant properties of cervical cancer cells via targeting miR-642a-3p/NR2F1 axis
by: Lingyan Zhang, et al.
Published: (2022-10-01)

Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands
by: Srijana Upadhyay, et al.
Published: (2024-02-01)

Effect of NeuroAid Supplement on the NR1 and NR2 Protein Levels in Prefrontal Cortex and Striatum of Male Rats With Total Sleep Deprivation
by: Arezo Naserkheil, et al.
Published: (2022-03-01)

The Value of Serum NR2 Antibody in Prediction of Post-Cardiopulmonary Resuscitation Survival
by: Ali Bidari, et al.
Published: (2018-12-01)

The Value of Serum NR2 Antibody in Prediction of Post-Cardiopulmonary Resuscitation Survival
by: Ali Bidari, et al.
Published: (2015-07-01)

Orphan nuclear receptor NR4A2 inhibits hepatic stellate cell proliferation through MAPK pathway in liver fibrosis
by: Pengguo Chen, et al.
Published: (2015-12-01)

Compliance with Good Manufacturing Practice in the Assessment of Immunomodulation Potential of Clinical Grade Multipotent Mesenchymal Stromal Cells Derived from Wharton’s Jelly
by: Marta Grau-Vorster, et al.
Published: (2019-05-01)

5-Aza-cdR improves learning capacity and memory through enhancing NR2B phosphorylation level in hippocampus of mice
by: LIU Xiao-lei, WANG Qiang, ZHANG Xiao-lu, SHAO Guo, JIANG Shu-yuan
Published: (2021-08-01)

Nr4a1 marks a distinctive ILC2 activation subset in the mouse inflammatory lung
by: Shasha Xu, et al.
Published: (2023-10-01)

NR2F2 alleviates pulmonary fibrosis by inhibition of epithelial cell senescence
by: Ruyan Wan, et al.
Published: (2024-04-01)

The role of NR2C2 in the prolactinomas
by: Zhuang Wang, et al.
Published: (2018-08-01)

Regulation of Circadian Genes Nr1d1 and Nr1d2 in Sex-Different Manners during Liver Aging
by: Sang Gyun Noh, et al.
Published: (2022-09-01)

Function of Nr4a Orphan Nuclear Receptors in Proliferation, Apoptosis and Fuel Utilization Across Tissues
by: Jacob A. Herring, et al.
Published: (2019-11-01)

The Distribution, Expression Patterns and Functional Analysis of NR1D1 and NR4A2 in the Reproductive Axis Tissues of the Male Tianzhu White Yak
by: Lijun Dai, et al.
Published: (2021-10-01)

Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen Presentation and Viral Response
by: David E. Phelan, et al.
Published: (2021-06-01)

Interaction between Macrophages and Human Mesenchymal Stromal Cells Derived from Bone Marrow and Wharton’s Jelly—A Comparative Study
by: Marta Dymowska, et al.
Published: (2021-11-01)