Electrospun Scaffolds as Cell Culture Substrates for the Cultivation of an In Vitro Blood–Brain Barrier Model Using Human Induced Pluripotent Stem Cells

Electrospun Scaffolds as Cell Culture Substrates for the Cultivation of an In Vitro Blood–Brain Barrier Model Using Human Induced Pluripotent Stem Cells

The human blood–brain barrier (BBB) represents the interface of microvasculature and the central nervous system, regulating the transport of nutrients and protecting the brain from external threats. To gain a deeper understanding of (patho)physiological processes affecting the BBB, sophisticated mod...

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Bibliographic Details
Main Authors: Felix Rohde, Karin Danz, Nathalie Jung, Sylvia Wagner, Maike Windbergs
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
electrospinning
blood–brain barrier
human induced pluripotent stem cells
tissue engineering
extracellular matrix
basement membrane
Online Access:https://www.mdpi.com/1999-4923/14/6/1308

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