OB-fold Families of Genome Guardians: A Universal Theme Constructed From the Small β-barrel Building Block

OB-fold Families of Genome Guardians: A Universal Theme Constructed From the Small β-barrel Building Block

The maintenance of genome stability requires the coordinated actions of multiple proteins and protein complexes, that are collectively known as genome guardians. Within this broadly defined family is a subset of proteins that contain oligonucleotide/oligosaccharide-binding folds (OB-fold). While OB-...

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Bibliographic Details
Main Author: Piero R. Bianco
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
OB-fold
SH3 domain
PXXP
genome guardian
SBB family
MCM
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.784451/full

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