Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study.
OBJECTIVE:To investigate response inhibition after total sleep deprivation (TSD) and the restorative effects of one night of recovery sleep (RS). METHODS:Fourteen healthy male participants performed a visual Go/NoGo task, and electroencephalogram recordings were conducted at five time points: (1) ba...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4684334?pdf=render |
| _version_ | 1811205391301738496 |
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| author | Xiao Jin Enmao Ye Jianlin Qi Lubin Wang Yu Lei Pinhong Chen Guiyun Mi Feng Zou Yongcong Shao Zheng Yang |
| author_facet | Xiao Jin Enmao Ye Jianlin Qi Lubin Wang Yu Lei Pinhong Chen Guiyun Mi Feng Zou Yongcong Shao Zheng Yang |
| author_sort | Xiao Jin |
| collection | DOAJ |
| description | OBJECTIVE:To investigate response inhibition after total sleep deprivation (TSD) and the restorative effects of one night of recovery sleep (RS). METHODS:Fourteen healthy male participants performed a visual Go/NoGo task, and electroencephalogram recordings were conducted at five time points: (1) baseline, (2) after 12 h of TSD, (3) after 24 h of TSD, (4) after 36 h of TSD, and (5) following 8 h of RS. The dynamic changes in response inhibition during TSD and after 8 h of RS were investigated by examining the NoGo-N2 and NoGo-P3 event-related potential components. RESULTS:Compared with baseline, NoGo-P3 amplitudes were decreased, while the NoGo-N2 latency increased along with the awake time prolonged. NoGo anteriorization, which was minimized after 24 h of TSD, progressively decreased with increasing TSD. After 8 h of RS, recoveries of both the NoGo-P3 amplitude and NoGo-N2 latency in the prefrontal cortex were observed compared with the values after 36 h of TSD. CONCLUSION:TSD induced a dose-dependent functional decline in the response inhibition of NoGo-N2 and NoGo-P3 on prefrontal cortex activation, and 8 h of RS resulted in recovery or maintenance of the response inhibition. However, it was not restored to baseline levels. LIMITATIONS:Participants were chosen male college students only, thus the findings cannot be generalized to older people and women. Additionally, the sample size was small, and, thus, speculations on the meaning of the results of this study should be cautious. The EEG continuous recording should be employed to monitor the decline of alertness following TSD. |
| first_indexed | 2024-04-12T03:31:53Z |
| format | Article |
| id | doaj.art-0e011d4e41b146b79c794ca829ca56fe |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T03:31:53Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-0e011d4e41b146b79c794ca829ca56fe2022-12-22T03:49:32ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-011012e014236110.1371/journal.pone.0142361Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study.Xiao JinEnmao YeJianlin QiLubin WangYu LeiPinhong ChenGuiyun MiFeng ZouYongcong ShaoZheng YangOBJECTIVE:To investigate response inhibition after total sleep deprivation (TSD) and the restorative effects of one night of recovery sleep (RS). METHODS:Fourteen healthy male participants performed a visual Go/NoGo task, and electroencephalogram recordings were conducted at five time points: (1) baseline, (2) after 12 h of TSD, (3) after 24 h of TSD, (4) after 36 h of TSD, and (5) following 8 h of RS. The dynamic changes in response inhibition during TSD and after 8 h of RS were investigated by examining the NoGo-N2 and NoGo-P3 event-related potential components. RESULTS:Compared with baseline, NoGo-P3 amplitudes were decreased, while the NoGo-N2 latency increased along with the awake time prolonged. NoGo anteriorization, which was minimized after 24 h of TSD, progressively decreased with increasing TSD. After 8 h of RS, recoveries of both the NoGo-P3 amplitude and NoGo-N2 latency in the prefrontal cortex were observed compared with the values after 36 h of TSD. CONCLUSION:TSD induced a dose-dependent functional decline in the response inhibition of NoGo-N2 and NoGo-P3 on prefrontal cortex activation, and 8 h of RS resulted in recovery or maintenance of the response inhibition. However, it was not restored to baseline levels. LIMITATIONS:Participants were chosen male college students only, thus the findings cannot be generalized to older people and women. Additionally, the sample size was small, and, thus, speculations on the meaning of the results of this study should be cautious. The EEG continuous recording should be employed to monitor the decline of alertness following TSD.http://europepmc.org/articles/PMC4684334?pdf=render |
| spellingShingle | Xiao Jin Enmao Ye Jianlin Qi Lubin Wang Yu Lei Pinhong Chen Guiyun Mi Feng Zou Yongcong Shao Zheng Yang Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study. PLoS ONE |
| title | Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study. |
| title_full | Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study. |
| title_fullStr | Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study. |
| title_full_unstemmed | Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study. |
| title_short | Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study. |
| title_sort | recovery sleep reverses impaired response inhibition due to sleep restriction evidence from a visual event related potentials study |
| url | http://europepmc.org/articles/PMC4684334?pdf=render |
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