The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regeneration
This study aimed to determine the effects of bovine amniotic fluid combined with bone graft in treating peri-implant bone defects with guided bone regeneration. Twenty female Sprague–Dawley rats were divided into two groups. Bone sockets with a diameter of 4 mm in the coronal part and a diameter of...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kafkas University, Faculty of Veterinary Medicine
2023-09-01
|
| Series: | Kafkas Universitesi Veteriner Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://vetdergikafkas.org/pdf.php?id=3032 |
| _version_ | 1797403817863544832 |
|---|---|
| author | Ozmen ISTEK Murat TANRISEVER Hatice EROKSUZ Burak KARABULUT Erhan Cahit OZCAN Muhammet Bahattin BINGUL Rıdvan GULER Serkan DUNDAR |
| author_facet | Ozmen ISTEK Murat TANRISEVER Hatice EROKSUZ Burak KARABULUT Erhan Cahit OZCAN Muhammet Bahattin BINGUL Rıdvan GULER Serkan DUNDAR |
| author_sort | Ozmen ISTEK |
| collection | DOAJ |
| description | This study aimed to determine the effects of bovine amniotic fluid combined with bone
graft in treating peri-implant bone defects with guided bone regeneration. Twenty female
Sprague–Dawley rats were divided into two groups. Bone sockets with a diameter of 4
mm in the coronal part and a diameter of 2.5 mm in the apical part of the implant were
created into the corticocancellous bone in the metaphyseal parts of the right tibia bones
of all subjects. Implants with a length of 4 mm and a diameter of 2.5 mm were placed in
the bone sockets. In the sham surgery group (n = 10) was the circumferential bone defect
equivalent to half of the 4-mm implant length, which occurred between the implant
and the bone, filled with bovine xenograft. Bovine xenografts were filled with amniotic
fluid mixture in the experimental group (n = 10). After 8 weeks of recovery, all rats were
sacrificed. The implants were extracted from the soft tissues and the surrounding bone.
Subsequently, the bones were decalcified and prepared for histological analysis. The
percentage of newly regenerated bone (NRB) formation and fibrosis in the bone defect
area around the implant was calculated from all sections. NRB was found in 37.4±4.4%
of controls and 41.4±2.63% of test animals (P<0.05 and P=0.024, respectively). Fibrosis
formation was found at a rate of 38.6±5.06% in the control group and 33.2±5.38% in the
test group (P<0.05 and P=0.033, respectively). It was considered that combining bovine
amniotic fluid with bone transplant could be a useful way of treating bone abnormalities. |
| first_indexed | 2024-03-09T02:43:55Z |
| format | Article |
| id | doaj.art-0e0263edbde049158838da64169245f1 |
| institution | Directory Open Access Journal |
| issn | 1309-2251 |
| language | English |
| last_indexed | 2024-03-09T02:43:55Z |
| publishDate | 2023-09-01 |
| publisher | Kafkas University, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Kafkas Universitesi Veteriner Fakültesi Dergisi |
| spelling | doaj.art-0e0263edbde049158838da64169245f12023-12-05T21:27:25ZengKafkas University, Faculty of Veterinary MedicineKafkas Universitesi Veteriner Fakültesi Dergisi1309-22512023-09-0129555155610.9775/kvfd.2023.300313032The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regenerationOzmen ISTEK0Murat TANRISEVER1Hatice EROKSUZ2Burak KARABULUT3Erhan Cahit OZCAN4Muhammet Bahattin BINGUL5Rıdvan GULER6Serkan DUNDAR7Muş Alparslan University, Faculty of Health Sciences, Department of Nursing, TR-49250 Muş - TÜRKİYEFirat University, Faculty of Veterinary Medicine, Department of Surgery, TR-23119 Elazığ - TÜRKİYEFirat University, Faculty of Veterinary Medicine, Department of Pathology, TR-23119 Elazığ - TÜRKİYEFirat University, Faculty of Veterinary Medicine, Department of Pathology, TR-23119 Elazığ - TÜRKİYEFirat University, Faculty of Medicine, Department of Esthetic, Plastic and Reconstructive Surgery, TR-23119 Elazığ - TÜRKİYEHarran University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, TR-63290 Şanlıurfa - TÜRKİYEDicle University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, TR-21280 Diyarbakır - TÜRKİYEFirat University, Faculty of Dentistry, Department of Peridontology, TR-23119 Elazığ - TÜRKİYEThis study aimed to determine the effects of bovine amniotic fluid combined with bone graft in treating peri-implant bone defects with guided bone regeneration. Twenty female Sprague–Dawley rats were divided into two groups. Bone sockets with a diameter of 4 mm in the coronal part and a diameter of 2.5 mm in the apical part of the implant were created into the corticocancellous bone in the metaphyseal parts of the right tibia bones of all subjects. Implants with a length of 4 mm and a diameter of 2.5 mm were placed in the bone sockets. In the sham surgery group (n = 10) was the circumferential bone defect equivalent to half of the 4-mm implant length, which occurred between the implant and the bone, filled with bovine xenograft. Bovine xenografts were filled with amniotic fluid mixture in the experimental group (n = 10). After 8 weeks of recovery, all rats were sacrificed. The implants were extracted from the soft tissues and the surrounding bone. Subsequently, the bones were decalcified and prepared for histological analysis. The percentage of newly regenerated bone (NRB) formation and fibrosis in the bone defect area around the implant was calculated from all sections. NRB was found in 37.4±4.4% of controls and 41.4±2.63% of test animals (P<0.05 and P=0.024, respectively). Fibrosis formation was found at a rate of 38.6±5.06% in the control group and 33.2±5.38% in the test group (P<0.05 and P=0.033, respectively). It was considered that combining bovine amniotic fluid with bone transplant could be a useful way of treating bone abnormalities.https://vetdergikafkas.org/pdf.php?id=3032bone graftbovine amniotic fluidguided bone regenerationperi-implant bone defecttibial bone |
| spellingShingle | Ozmen ISTEK Murat TANRISEVER Hatice EROKSUZ Burak KARABULUT Erhan Cahit OZCAN Muhammet Bahattin BINGUL Rıdvan GULER Serkan DUNDAR The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regeneration Kafkas Universitesi Veteriner Fakültesi Dergisi bone graft bovine amniotic fluid guided bone regeneration peri-implant bone defect tibial bone |
| title | The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regeneration |
| title_full | The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regeneration |
| title_fullStr | The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regeneration |
| title_full_unstemmed | The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regeneration |
| title_short | The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regeneration |
| title_sort | histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri implant bone regeneration |
| topic | bone graft bovine amniotic fluid guided bone regeneration peri-implant bone defect tibial bone |
| url | https://vetdergikafkas.org/pdf.php?id=3032 |
| work_keys_str_mv | AT ozmenistek thehistopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT murattanrisever thehistopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT haticeeroksuz thehistopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT burakkarabulut thehistopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT erhancahitozcan thehistopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT muhammetbahattinbingul thehistopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT rıdvanguler thehistopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT serkandundar thehistopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT ozmenistek histopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT murattanrisever histopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT haticeeroksuz histopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT burakkarabulut histopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT erhancahitozcan histopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT muhammetbahattinbingul histopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT rıdvanguler histopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration AT serkandundar histopathologicalevaluationofeffectsofapplicationofthebovineamnioticfluidwithgraftonperiimplantboneregeneration |