Proj2Proj: self-supervised low-dose CT reconstruction

In Computed Tomography (CT) imaging, one of the most serious concerns has always been ionizing radiation. Several approaches have been proposed to reduce the dose level without compromising the image quality. With the emergence of deep learning, thanks to the increasing availability of computational...

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Main Authors: Mehmet Ozan Unal, Metin Ertas, Isa Yildirim
Format: Article
Language:English
Published: PeerJ Inc. 2024-02-01
Series:PeerJ Computer Science
Subjects:
Online Access:https://peerj.com/articles/cs-1849.pdf
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author Mehmet Ozan Unal
Metin Ertas
Isa Yildirim
author_facet Mehmet Ozan Unal
Metin Ertas
Isa Yildirim
author_sort Mehmet Ozan Unal
collection DOAJ
description In Computed Tomography (CT) imaging, one of the most serious concerns has always been ionizing radiation. Several approaches have been proposed to reduce the dose level without compromising the image quality. With the emergence of deep learning, thanks to the increasing availability of computational power and huge datasets, data-driven methods have recently received a lot of attention. Deep learning based methods have also been applied in various ways to address the low-dose CT reconstruction problem. However, the success of these methods largely depends on the availability of labeled data. On the other hand, recent studies showed that training can be done successfully without the need for labeled datasets. In this study, a training scheme was defined to use low-dose projections as their own training targets. The self-supervision principle was applied in the projection domain. The parameters of a denoiser neural network were optimized through self-supervised training. It was shown that our method outperformed both traditional and compressed sensing-based iterative methods, and deep learning based unsupervised methods, in the reconstruction of analytic CT phantoms and human CT images in low-dose CT imaging. Our method’s reconstruction quality is also comparable to a well-known supervised method.
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spelling doaj.art-0e03bb828f8c486aa7d9442d7e29f57c2024-03-02T15:05:12ZengPeerJ Inc.PeerJ Computer Science2376-59922024-02-0110e184910.7717/peerj-cs.1849Proj2Proj: self-supervised low-dose CT reconstructionMehmet Ozan Unal0Metin Ertas1Isa Yildirim2Department of Electronics and Communication Engineering, Istanbul Technical University, Istanbul, TurkeyDepartment of Electrical and Electronics Engineering, Istanbul University-Cerrahpasa, Istanbul, TurkeyDepartment of Electronics and Communication Engineering, Istanbul Technical University, Istanbul, TurkeyIn Computed Tomography (CT) imaging, one of the most serious concerns has always been ionizing radiation. Several approaches have been proposed to reduce the dose level without compromising the image quality. With the emergence of deep learning, thanks to the increasing availability of computational power and huge datasets, data-driven methods have recently received a lot of attention. Deep learning based methods have also been applied in various ways to address the low-dose CT reconstruction problem. However, the success of these methods largely depends on the availability of labeled data. On the other hand, recent studies showed that training can be done successfully without the need for labeled datasets. In this study, a training scheme was defined to use low-dose projections as their own training targets. The self-supervision principle was applied in the projection domain. The parameters of a denoiser neural network were optimized through self-supervised training. It was shown that our method outperformed both traditional and compressed sensing-based iterative methods, and deep learning based unsupervised methods, in the reconstruction of analytic CT phantoms and human CT images in low-dose CT imaging. Our method’s reconstruction quality is also comparable to a well-known supervised method.https://peerj.com/articles/cs-1849.pdfDeep learningLow-dose CTImage reconstructionSelf-supervised learning
spellingShingle Mehmet Ozan Unal
Metin Ertas
Isa Yildirim
Proj2Proj: self-supervised low-dose CT reconstruction
PeerJ Computer Science
Deep learning
Low-dose CT
Image reconstruction
Self-supervised learning
title Proj2Proj: self-supervised low-dose CT reconstruction
title_full Proj2Proj: self-supervised low-dose CT reconstruction
title_fullStr Proj2Proj: self-supervised low-dose CT reconstruction
title_full_unstemmed Proj2Proj: self-supervised low-dose CT reconstruction
title_short Proj2Proj: self-supervised low-dose CT reconstruction
title_sort proj2proj self supervised low dose ct reconstruction
topic Deep learning
Low-dose CT
Image reconstruction
Self-supervised learning
url https://peerj.com/articles/cs-1849.pdf
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AT metinertas proj2projselfsupervisedlowdosectreconstruction
AT isayildirim proj2projselfsupervisedlowdosectreconstruction