Juvenile depletion of microglia reduces orientation but not high spatial frequency selectivity in mouse V1

Abstract Microglia contain multiple mechanisms that shape the synaptic landscape during postnatal development. Whether the synaptic changes mediated by microglia reflect the developmental refinement of neuronal responses in sensory cortices, however, remains poorly understood. In postnatal life, the...

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Bibliographic Details
Main Authors: Dario X. Figueroa Velez, Miguel Arreola, Carey Y. L. Huh, Kim Green, Sunil P. Gandhi
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15503-0