Variation in the MC4R gene is associated with bone phenotypes in elderly Swedish women.
Osteoporosis is characterized by reduced bone mineral density (BMD) and increased fracture risk. Fat mass is a determinant of bone strength and both phenotypes have a strong genetic component. In this study, we examined the association between obesity associated polymorphisms (SNPs) with body compos...
Main Authors: | Gaurav Garg, Jitender Kumar, Fiona E McGuigan, Martin Ridderstråle, Paul Gerdhem, Holger Luthman, Kristina Åkesson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3916440?pdf=render |
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