Needle and syringe programs in Yunnan, China yield health and financial return

<p>Abstract</p> <p>Background</p> <p>As a harm reduction strategy in response to HIV epidemics needle and syringes programs (NSPs) were initiated throughout China in 2002. The effectiveness of NSPs in reducing the spread of infection in such an established epidemic is u...

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Main Authors: Xun Zhuang, Wu Zunyou, Yap Lorraine, Zhang Lei, Wilson David P
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Public Health
Subjects:
Online Access:http://www.biomedcentral.com/1471-2458/11/250
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author Xun Zhuang
Wu Zunyou
Yap Lorraine
Zhang Lei
Wilson David P
author_facet Xun Zhuang
Wu Zunyou
Yap Lorraine
Zhang Lei
Wilson David P
author_sort Xun Zhuang
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>As a harm reduction strategy in response to HIV epidemics needle and syringes programs (NSPs) were initiated throughout China in 2002. The effectiveness of NSPs in reducing the spread of infection in such an established epidemic is unknown. In this study we use data from Yunnan province, the province most affected by HIV in China, to (1) estimate the population benefits in terms of infections prevented due to the programs; (2) calculate the cost-effectiveness of NSPs.</p> <p>Methods</p> <p>We developed a mathematical transmission model, informed by detailed behavioral and program data, which accurately reflected the unique HIV epidemiology among Yunnan injecting drug users (IDUs) in the presence of NSPs. We then used the model to estimate the likely epidemiological and clinical outcomes without NSPs and conducted a health economics analysis to determine the cost-effectiveness of the program.</p> <p>Results</p> <p>It is estimated that NSPs in Yunnan have averted approximately 16-20% (5,200-7,500 infections) of the expected HIV cases since 2002 and led to gains of 1,300-1,900 DALYs. The total $1.04 million spending on NSPs from 2002 to 2008 has resulted in an estimated cost-saving over this period of $1.38-$1.97 million due to the prevention of HIV and the associated costs of care and management.</p> <p>Conclusion</p> <p>NSPs are not only cost-effective but cost-saving in Yunnan. Significant scale-up of NSPs interventions across China and removal of the societal and political barriers that compromise the effects of NSPs should be a health priority of the Chinese government.</p>
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spelling doaj.art-0e098f9a15d4437d937210412336eb0c2022-12-22T02:04:27ZengBMCBMC Public Health1471-24582011-04-0111125010.1186/1471-2458-11-250Needle and syringe programs in Yunnan, China yield health and financial returnXun ZhuangWu ZunyouYap LorraineZhang LeiWilson David P<p>Abstract</p> <p>Background</p> <p>As a harm reduction strategy in response to HIV epidemics needle and syringes programs (NSPs) were initiated throughout China in 2002. The effectiveness of NSPs in reducing the spread of infection in such an established epidemic is unknown. In this study we use data from Yunnan province, the province most affected by HIV in China, to (1) estimate the population benefits in terms of infections prevented due to the programs; (2) calculate the cost-effectiveness of NSPs.</p> <p>Methods</p> <p>We developed a mathematical transmission model, informed by detailed behavioral and program data, which accurately reflected the unique HIV epidemiology among Yunnan injecting drug users (IDUs) in the presence of NSPs. We then used the model to estimate the likely epidemiological and clinical outcomes without NSPs and conducted a health economics analysis to determine the cost-effectiveness of the program.</p> <p>Results</p> <p>It is estimated that NSPs in Yunnan have averted approximately 16-20% (5,200-7,500 infections) of the expected HIV cases since 2002 and led to gains of 1,300-1,900 DALYs. The total $1.04 million spending on NSPs from 2002 to 2008 has resulted in an estimated cost-saving over this period of $1.38-$1.97 million due to the prevention of HIV and the associated costs of care and management.</p> <p>Conclusion</p> <p>NSPs are not only cost-effective but cost-saving in Yunnan. Significant scale-up of NSPs interventions across China and removal of the societal and political barriers that compromise the effects of NSPs should be a health priority of the Chinese government.</p>http://www.biomedcentral.com/1471-2458/11/250HIVinjecting drug usersYunnanChinaneedle-syringe programsmathematical modelhealth economics
spellingShingle Xun Zhuang
Wu Zunyou
Yap Lorraine
Zhang Lei
Wilson David P
Needle and syringe programs in Yunnan, China yield health and financial return
BMC Public Health
HIV
injecting drug users
Yunnan
China
needle-syringe programs
mathematical model
health economics
title Needle and syringe programs in Yunnan, China yield health and financial return
title_full Needle and syringe programs in Yunnan, China yield health and financial return
title_fullStr Needle and syringe programs in Yunnan, China yield health and financial return
title_full_unstemmed Needle and syringe programs in Yunnan, China yield health and financial return
title_short Needle and syringe programs in Yunnan, China yield health and financial return
title_sort needle and syringe programs in yunnan china yield health and financial return
topic HIV
injecting drug users
Yunnan
China
needle-syringe programs
mathematical model
health economics
url http://www.biomedcentral.com/1471-2458/11/250
work_keys_str_mv AT xunzhuang needleandsyringeprogramsinyunnanchinayieldhealthandfinancialreturn
AT wuzunyou needleandsyringeprogramsinyunnanchinayieldhealthandfinancialreturn
AT yaplorraine needleandsyringeprogramsinyunnanchinayieldhealthandfinancialreturn
AT zhanglei needleandsyringeprogramsinyunnanchinayieldhealthandfinancialreturn
AT wilsondavidp needleandsyringeprogramsinyunnanchinayieldhealthandfinancialreturn