Efficacy of an Optimised Bacteriophage Cocktail to Clear Clostridium difficile in a Batch Fermentation Model

Efficacy of an Optimised Bacteriophage Cocktail to Clear Clostridium difficile in a Batch Fermentation Model

Clostridium difficile infection (CDI) is a major cause of infectious diarrhea. Conventional antibiotics are not universally effective for all ribotypes, and can trigger dysbiosis, resistance and recurrent infection. Thus, novel therapeutics are needed to replace and/or supplement the current antibio...

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Bibliographic Details
Main Authors: Janet Y. Nale, Tamsin A. Redgwell, Andrew Millard, Martha R. J. Clokie
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Antibiotics
Subjects:
Clostridium difficile
Clostridium difficile infection
bacteriophages
phage therapy
microbiome
in vitro fermentation model
Online Access:http://www.mdpi.com/2079-6382/7/1/13

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