GTO: A toolkit to unify pipelines in genomic and proteomic research

Next-generation sequencing triggered the production of a massive volume of publicly available data and the development of new specialised tools. These tools are dispersed over different frameworks, making the management and analyses of the data a challenging task. Additionally, new targeted tools ar...

Full description

Bibliographic Details
Main Authors: João R. Almeida, Armando J. Pinho, José L. Oliveira, Olga Fajarda, Diogo Pratas
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:SoftwareX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352711020301473
_version_ 1818393835991990272
author João R. Almeida
Armando J. Pinho
José L. Oliveira
Olga Fajarda
Diogo Pratas
author_facet João R. Almeida
Armando J. Pinho
José L. Oliveira
Olga Fajarda
Diogo Pratas
author_sort João R. Almeida
collection DOAJ
description Next-generation sequencing triggered the production of a massive volume of publicly available data and the development of new specialised tools. These tools are dispersed over different frameworks, making the management and analyses of the data a challenging task. Additionally, new targeted tools are needed, given the dynamics and specificities of the field. We present GTO, a comprehensive toolkit designed to unify pipelines in genomic and proteomic research, which combines specialised tools for analysis, simulation, compression, development, visualisation, and transformation of the data. This toolkit combines novel tools with a modular architecture, being an excellent platform for experimental scientists, as well as a useful resource for teaching bioinformatics enquiry to students in life sciences. GTO is implemented in C language and is available, under the MIT license, at https://bioinformatics.ua.pt/gto.
first_indexed 2024-12-14T05:51:38Z
format Article
id doaj.art-0e0cf3628ade4db2b651460067238538
institution Directory Open Access Journal
issn 2352-7110
language English
last_indexed 2024-12-14T05:51:38Z
publishDate 2020-07-01
publisher Elsevier
record_format Article
series SoftwareX
spelling doaj.art-0e0cf3628ade4db2b6514600672385382022-12-21T23:14:42ZengElsevierSoftwareX2352-71102020-07-0112100535GTO: A toolkit to unify pipelines in genomic and proteomic researchJoão R. Almeida0Armando J. Pinho1José L. Oliveira2Olga Fajarda3Diogo Pratas4Department of Electronics, Telecommunications and Informatics (DETI/IEETA), University of Aveiro, Aveiro, Portugal; Department of Information and Communications Technologies, University of A Coruña, A Coruña, Spain; Corresponding author at: Department of Electronics, Telecommunications and Informatics (DETI/IEETA), University of Aveiro, Aveiro, Portugal.Department of Electronics, Telecommunications and Informatics (DETI/IEETA), University of Aveiro, Aveiro, PortugalDepartment of Electronics, Telecommunications and Informatics (DETI/IEETA), University of Aveiro, Aveiro, PortugalDepartment of Electronics, Telecommunications and Informatics (DETI/IEETA), University of Aveiro, Aveiro, PortugalDepartment of Electronics, Telecommunications and Informatics (DETI/IEETA), University of Aveiro, Aveiro, Portugal; Department of Virology, University of Helsinki, Helsinki, FinlandNext-generation sequencing triggered the production of a massive volume of publicly available data and the development of new specialised tools. These tools are dispersed over different frameworks, making the management and analyses of the data a challenging task. Additionally, new targeted tools are needed, given the dynamics and specificities of the field. We present GTO, a comprehensive toolkit designed to unify pipelines in genomic and proteomic research, which combines specialised tools for analysis, simulation, compression, development, visualisation, and transformation of the data. This toolkit combines novel tools with a modular architecture, being an excellent platform for experimental scientists, as well as a useful resource for teaching bioinformatics enquiry to students in life sciences. GTO is implemented in C language and is available, under the MIT license, at https://bioinformatics.ua.pt/gto.http://www.sciencedirect.com/science/article/pii/S2352711020301473Genomic ToolkitProteomic ToolkitNext-generation sequencing
spellingShingle João R. Almeida
Armando J. Pinho
José L. Oliveira
Olga Fajarda
Diogo Pratas
GTO: A toolkit to unify pipelines in genomic and proteomic research
SoftwareX
Genomic Toolkit
Proteomic Toolkit
Next-generation sequencing
title GTO: A toolkit to unify pipelines in genomic and proteomic research
title_full GTO: A toolkit to unify pipelines in genomic and proteomic research
title_fullStr GTO: A toolkit to unify pipelines in genomic and proteomic research
title_full_unstemmed GTO: A toolkit to unify pipelines in genomic and proteomic research
title_short GTO: A toolkit to unify pipelines in genomic and proteomic research
title_sort gto a toolkit to unify pipelines in genomic and proteomic research
topic Genomic Toolkit
Proteomic Toolkit
Next-generation sequencing
url http://www.sciencedirect.com/science/article/pii/S2352711020301473
work_keys_str_mv AT joaoralmeida gtoatoolkittounifypipelinesingenomicandproteomicresearch
AT armandojpinho gtoatoolkittounifypipelinesingenomicandproteomicresearch
AT joseloliveira gtoatoolkittounifypipelinesingenomicandproteomicresearch
AT olgafajarda gtoatoolkittounifypipelinesingenomicandproteomicresearch
AT diogopratas gtoatoolkittounifypipelinesingenomicandproteomicresearch